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PDE1A Produits

(Phosphodiesterase 1A (PDE1A))

Catégories

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1\; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]\; Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009].

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Catégories PDE1A en vedette

PDE1A Anticorps

High quality antibodies with extensive validation data.

PDE1A Kits ELISA

Reliable ELISA kits for a wide range of species.

PDE1A Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PDE1A recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
N° du produit ABIN7441283
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Dog, Human, Mouse, Rat
Application WB
Validations
  • (4)
N° du produit ABIN2785487
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
N° du produit ABIN6264086
Quantité 100 μL
Fiche technique Fiche technique

PDE1A recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958529
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN5657765
Quantité 96 tests
Fiche technique Fiche technique

PDE1A recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314449
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314451
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7408210
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PDE1A

Rajagopal, Nalli, Kumar, Bhattacharya, Hu, Mahavadi, Grider, Murthy: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." dans: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).

Kedia, Ückert, Oelke, Sonnenberg, Sohn, Kuczyk, Hedlund: "Expression and distribution of phosphodiesterase isoenzymes in the human male urethra." dans: Urology, Vol. 85, Issue 4, pp. 964.e1-6, (2015) (PubMed).

Uckert, Albrecht, Kuczyk, Hedlund, Oelke: "Phosphodiesterase type 1, calcitonin gene-related peptide and vasoactive intestinal polypeptide are involved in the control of human vaginal arterial vessels." dans: European journal of obstetrics, gynecology, and reproductive biology, Vol. 169, Issue 2, pp. 283-6, (2014) (PubMed).

Yougbaré, Keravis, Abusnina, Decossas, Schall, Muller, Lugnier: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." dans: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).

Abusnina, Keravis, Yougbaré, Bronner, Lugnier: "Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1." dans: Molecular nutrition & food research, Vol. 55, Issue 11, pp. 1677-89, (2012) (PubMed).

Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." dans: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

Genders, Bradley, Rattigan, Richards: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." dans: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).

Cabanero, Laje, Detera-Wadleigh, McMahon: "Association study of phosphodiesterase genes in the Sequenced Treatment Alternatives to Relieve Depression sample." dans: Pharmacogenetics and genomics, Vol. 19, Issue 3, pp. 235-8, (2009) (PubMed).

Ortiz-Capisano, Liao, Ortiz, Beierwaltes: "Calcium-dependent phosphodiesterase 1C inhibits renin release from isolated juxtaglomerular cells." dans: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 297, Issue 5, pp. R1469-76, (2009) (PubMed).

Deplano, Giorgi, Maccarone, Santone, Nuccetelli, Basso, Bisti: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase during ontogenesis of chick retina." dans: Journal of neuroscience research, Vol. 86, Issue 5, pp. 1017-23, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à PDE1A

phosphodiesterase 1A (PDE1A), phosphodiesterase 1A, calmodulin-dependent (pde1a), phosphodiesterase 1A (pde1a), phosphodiesterase 1A, calmodulin-dependent (PDE1A), phosphodiesterase 1A (Pde1a), phosphodiesterase 1A, calmodulin-dependent (Pde1a), 3'-RACEclone8phosphodiesterase1A, 3-RACEclone8phosphodiesterase1A, AI987702, AW125737, CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A, PDE1, PDE1A

Protein level used designations for PDE1A

  • calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
  • calmodulin-activated cyclic nucleotide phosphodiesterase
  • phosphodiesterase 1A, calmodulin-dependent
  • calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A-like
  • cyclic nucleotide phosphodiesterase 1a
  • 61 kDa Cam-PDE
  • calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase
  • cam-PDE 1A
  • 3'-RACE clone 8 phosphodiesterase 1A
  • 3-RACE clone 8 phosphodiesterase 1A
  • calmodulin-dependent phosphodiesterase type 1
  • nucleotide phosphodiesterase, 3'-5'-cyclic
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