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PDE1C Produits

(phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM, Oct 2009].

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Catégories PDE1C en vedette

PDE1C Anticorps

High quality antibodies with extensive validation data.

PDE1C Kits ELISA

Reliable ELISA kits for a wide range of species.

PDE1C Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PDE1C recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IF
Validations
  • (1)
N° du produit ABIN7146420
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB
Validations
  • (1)
N° du produit ABIN6243943
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (1)
N° du produit ABIN7269300
Quantité 100 μL
Fiche technique Fiche technique

PDE1C recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969260
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969259
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958530
Quantité 96 tests
Fiche technique Fiche technique

PDE1C recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
N° du produit ABIN7197331
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3085620
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3123289
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PDE1C

Cesarini, Martini, Vitiani, Gravina, Di Agostino, Graziani, DAlessandris, Pallini, Larocca, Rossi, Jannini, Dolci: "Type 5 phosphodiesterase regulates glioblastoma multiforme aggressiveness and clinical outcome." dans: Oncotarget, Vol. 8, Issue 8, pp. 13223-13239, (2017) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." dans: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Yougbaré, Keravis, Abusnina, Decossas, Schall, Muller, Lugnier: "Cyclic GMP catabolism up-regulation in MRL/lpr lupus-prone mice is associated with organ remodeling." dans: Biochimica et biophysica acta, Vol. 1842, Issue 7, pp. 916-26, (2014) (PubMed).

Abusnina, Keravis, Yougbaré, Bronner, Lugnier: "Anti-proliferative effect of curcumin on melanoma cells is mediated by PDE1A inhibition that regulates the epigenetic integrator UHRF1." dans: Molecular nutrition & food research, Vol. 55, Issue 11, pp. 1677-89, (2012) (PubMed).

Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." dans: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

Genders, Bradley, Rattigan, Richards: "cGMP phosphodiesterase inhibition improves the vascular and metabolic actions of insulin in skeletal muscle." dans: American journal of physiology. Endocrinology and metabolism, Vol. 301, Issue 2, pp. E342-50, (2011) (PubMed).

Ortiz-Capisano, Liao, Ortiz, Beierwaltes: "Calcium-dependent phosphodiesterase 1C inhibits renin release from isolated juxtaglomerular cells." dans: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 297, Issue 5, pp. R1469-76, (2009) (PubMed).

Dong, Zitt, Auriga, Hatzelmann, Epstein: "Inhibition of PDE3, PDE4 and PDE7 potentiates glucocorticoid-induced apoptosis and overcomes glucocorticoid resistance in CEM T leukemic cells." dans: Biochemical pharmacology, Vol. 79, Issue 3, pp. 321-9, (2009) (PubMed).

Deplano, Giorgi, Maccarone, Santone, Nuccetelli, Basso, Bisti: "Gene expression and protein localization of calmodulin-dependent phosphodiesterase during ontogenesis of chick retina." dans: Journal of neuroscience research, Vol. 86, Issue 5, pp. 1017-23, (2008) (PubMed).

Murray, Patel, Suda, Zhang, Thistlethwaite, Yuan, Insel: "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 1, pp. L294-303, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à PDE1C

Phosphodiesterase 1c (Pde1c), phosphodiesterase 1C (PDE1C), calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (LOC724389), calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C (LOC100019026), phosphodiesterase 1C, calmodulin-dependent b (pde1cb), phosphodiesterase 1C (Pde1c), CG14940, CG14942, CG14943, CG14944, CG31757, CG31758, CG42325, CG44007, Dmel\\CG44007, Dmel_CG14940, Dmel_CG14943, Dmel_CG14944, Dmel_CG31757, Dmel_CG31758, Dmel_CG42325, GB13690, Hcam3, PDE1C, PDE1c

Protein level used designations for PDE1C

  • CG44007-PB
  • CG44007-PC
  • CG44007-PD
  • CG44007-PE
  • CG44007-PG
  • CG44007-PH
  • CG44007-PJ
  • CG44007-PK
  • Pde1c-PB
  • Pde1c-PC
  • Pde1c-PD
  • Pde1c-PE
  • Pde1c-PG
  • Pde1c-PH
  • Pde1c-PJ
  • Pde1c-PK
  • phosphodiesterase 1c
  • phosphodiesterase 1C, calmodulin-dependent 70kDa
  • calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
  • calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C-like
  • cam-PDE 1C
  • cyclic nucleotide phosphodiesterase 1 C
  • phosphodiesterase 1C calmodulin-dependent (70kD)
  • Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A)
  • hCam-3
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