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PDE4D Produits

(phosphodiesterase 4D, cAMP-Specific (PDE4D))
The protein encoded by this gene serves to anchor phosphodiesterase 4D to the Golgi/centrosome region of the cell. Defects in this gene may be a cause of myeloproliferative disorder (MBD) associated with eosinophilia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2010].

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Catégories PDE4D en vedette

PDE4D Anticorps

High quality antibodies with extensive validation data.

PDE4D Kits ELISA

Reliable ELISA kits for a wide range of species.

PDE4D Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PDE4D recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, EIA
Validations
  • (1)
  • (4)
N° du produit ABIN185530
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (3)
N° du produit ABIN2855885
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (3)
N° du produit ABIN3022337
Quantité 100 μL
Fiche technique Fiche technique

PDE4D recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969263
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958534
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380247
Quantité 2 x 96 tests
Fiche technique Fiche technique

PDE4D recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
  • (1)
N° du produit ABIN1782353
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314469
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7398548
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PDE4D

Cao, Wang, Liao, Zhou, Liao, Zeng, He, Chen, He, Li, Lu: "Inactivation of oncogenic cAMP-specific phosphodiesterase 4D by miR-139-5p in response to p53 activation." dans: eLife, Vol. 5, (2016) (PubMed).

Massimi, Cardarelli, Galli, Giardi, Ragusa, Panera, Cinque, Cifone, Biagioni, Giorgi: "Increase of Intracellular Cyclic AMP by PDE4 Inhibitors Affects HepG2 Cell Cycle Progression and Survival." dans: Journal of cellular biochemistry, Vol. 118, Issue 6, pp. 1401-1411, (2016) (PubMed).

Petersen, Kristensen, Jeppesen, Grøndahl, Wissing, Macklon, Andersen: "Distribution and function of 3',5'-Cyclic-AMP phosphodiesterases in the human ovary." dans: Molecular and cellular endocrinology, Vol. 403, pp. 10-20, (2015) (PubMed).

Guo, Lin, Zhao, Zhang, Wei, Wang, Wang: "Etazolate abrogates the lipopolysaccharide (LPS)-induced downregulation of the cAMP/pCREB/BDNF signaling, neuroinflammatory response and depressive-like behavior in mice." dans: Neuroscience, Vol. 263, pp. 1-14, (2014) (PubMed).

Zhai, Chang, Wei, Liu, Leblais, Fischmeister, Ji: "Phosphodiesterase types 3 and 4 regulate the phasic contraction of neonatal rat bladder smooth myocytes via distinct mechanisms." dans: Cellular signalling, Vol. 26, Issue 5, pp. 1001-10, (2014) (PubMed).

Dong, Guo, Ye, Hare: "Presynaptic inhibition by α2 receptor/adenylate cyclase/PDE4 complex at retinal rod bipolar synapse." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 28, pp. 9432-40, (2014) (PubMed).

Wang, Zhang, Liu, Zhao, Zhang, Yuan, An, Li, Wang, Qin, Wilson, ODonnell, Zhang, Li: "RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects." dans: British journal of pharmacology, Vol. 168, Issue 4, pp. 1001-14, (2013) (PubMed).

Michalski, Kanaji, Liu, Nogel, Wang, Basma, Nakanishi, Sato, Gunji, Fahrid, Nelson, Muller, Holz, Magnussen, Rabe, Toews, Rennard: "Attenuation of inhibitory prostaglandin E2 signaling in human lung fibroblasts is mediated by phosphodiesterase 4." dans: American journal of respiratory cell and molecular biology, Vol. 47, Issue 6, pp. 729-37, (2013) (PubMed).

Al-Tawashi, Jung, Liu, Su, Qin: "Protein implicated in nonsyndromic mental retardation regulates protein kinase A (PKA) activity." dans: The Journal of biological chemistry, Vol. 287, Issue 18, pp. 14644-58, (2012) (PubMed).

Abusnina, Alhosin, Keravis, Muller, Fuhrmann, Bronner, Lugnier: "Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in thymoquinone-induced acute lymphoblastic leukemia cell apoptosis." dans: Cellular signalling, Vol. 23, Issue 1, pp. 152-60, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à PDE4D

phosphodiesterase 4D (PDE4D), phosphodiesterase 4D interacting protein (PDE4DIP), phosphodiesterase 4D (pde4d), phosphodiesterase 4D interacting protein (Pde4dip), phosphodiesterase 4D, cAMP specific (Pde4d), phosphodiesterase 4D (Pde4d), phosphodiesterase 4D, cAMP-specific (Pde4d), phosphodiesterase 4D interacting protein (myomegalin) (Pde4dip), phosphodiesterase 4D, cAMP-specific (pde4d), 4732458A06Rik, 9430063L05Rik, 9630011N22Rik, ACRDYS2, C87016, CMYA2, D3Bwg1078e, D130016K21Rik, DPDE3, Dpde3, HSPDE4D, mKIAA0454, MMGL, PDE4DN2, PDE43, si:dkey-190g11.2, STRK1, Usmg4

Protein level used designations for PDE4D

  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • cAMP-specific phosphodiesterase PDE4D6
  • phosphodiesterase 4D, cAMP-specific (phosphodiesterase E3 dunce homolog, Drosophila)
  • cardiomyopathy-associated protein 2
  • myomegalin
  • phosphodiesterase 4D, cAMP-specific
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D-like
  • phosphodiesterase 4D-interacting protein
  • phosphodiesterase-binding protein clone 46
  • cAMP-specific phosphodiesterase 4D
  • cyclic AMP specific phosphodiesterase PDE4D5A
  • dunce
  • DPDE3
  • Phosphodiesterase 4D cAMP-specific (dunce
  • Phosphodiesterase 4D, cAMP-specific (dunce
  • cAMP-specific phosphodiesterase PDE4D
  • cAMP-specific phosphodiesterase splice variant PDE4D8
  • phosphodiesterase 4D, cAMP specific
  • hypothetical protein
  • phosphodiesterase E3 dunce homolog, Drosophila
  • upregulated during skeletal muscle growth 4
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