PDE5A Produits
(phosphodiesterase 5A, cGMP-Specific (PDE5A))
Catégories
This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
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Catégories PDE5A en vedette
PDE5A Anticorps
High quality antibodies with extensive validation data.
PDE5A Kits ELISA
Reliable ELISA kits for a wide range of species.
PDE5A Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PDE5A recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (3)
N° du produit
ABIN563735
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, FACS
Validations
- (4)
N° du produit
ABIN185350
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB, IHC
Validations
- (1)
- (2)
N° du produit
ABIN2789423
Quantité
100 μL
Fiche technique
Fiche technique
PDE5A recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969266
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969265
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958535
Quantité
96 tests
Fiche technique
Fiche technique
PDE5A recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314473
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7414600
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Cell-free protein synthesis (CFPS)
Validations
N° du produit
ABIN3094479
Quantité
250 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PDE5A
: "Novel effect of sildenafil on hair growth." dans: Biochemical and biophysical research communications, Vol. 505, Issue 3, pp. 685-691, (2018) (PubMed).: "PDE5 Exists in Human Neurons and is a Viable Therapeutic Target for Neurologic Disease." dans: Journal of Alzheimer's disease : JAD, Vol. 52, Issue 1, pp. 295-302, (2016) (PubMed).
: "Expression and Function of Phosphodiesterase Type 5 in Human Breast Cancer Cell Lines and Tissues: Implications for Targeted Therapy." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 22, Issue 9, pp. 2271-82, (2016) (PubMed).
: "A phosphodiesterase type-5 inhibitor, sildenafil, induces sperm capacitation and penetration into porcine oocytes in a chemically defined medium." dans: Theriogenology, Vol. 85, Issue 3, pp. 428-33, (2016) (PubMed).
: "Role of Ser102 and Ser104 as regulators of cGMP hydrolysis by PDE5A." dans: PLoS ONE, Vol. 9, Issue 9, pp. e107627, (2015) (PubMed).
: "Cytokine-induced S-nitrosylation of soluble guanylyl cyclase and expression of phosphodiesterase 1A contribute to dysfunction of longitudinal smooth muscle relaxation." dans: The Journal of pharmacology and experimental therapeutics, Vol. 352, Issue 3, pp. 509-18, (2015) (PubMed).
: "Expression and distribution of phosphodiesterase isoenzymes in the human male urethra." dans: Urology, Vol. 85, Issue 4, pp. 964.e1-6, (2015) (PubMed).
: "Phosphodiesterase 1 regulation is a key mechanism in vascular aging." dans: Clinical science (London, England : 1979), Vol. 129, Issue 12, pp. 1061-75, (2015) (PubMed).
: "Effect of sildenafil on skeletal and cardiac muscle in Becker muscular dystrophy." dans: Annals of neurology, Vol. 76, Issue 4, pp. 550-7, (2014) (PubMed).
: "Expression and distribution of key enzymes of the cyclic GMP signaling in the human clitoris: relation to phosphodiesterase type 5 (PDE5)." dans: International journal of impotence research, Vol. 23, Issue 5, pp. 206-12, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à PDE5A
phosphodiesterase 5A (PDE5A), phosphodiesterase 5A (Pde5a), phosphodiesterase 5A, cGMP-specific (Pde5a), phosphodiesterase 5A S homeolog (pde5a.S), phosphodiesterase 5A, cGMP-specific, b (pde5ab), phosphodiesterase 5A (pde5a), CGB-PDE, cgb-pde, Cgbpde, CN5A, cn5a, Cn5n, PDE5, Pde5, pde5, PDE5A, pde5a, Pde5a1, pde5a1, PDE5A2Protein level used designations for PDE5A
- cGMP-binding cGMP-specific 3',5'-cyclic nucleotide phosphodiesterase
- cGMP-specific 3',5'-cyclic phosphodiesterase
- cGMP-specific phosphodiesterase PDE5A2
- cGMP-specific phosphodiesterase type 5A
- phosphodiesterase isozyme 5
- CGB-PDE
- cGMP-binding cGMP specific phosphodiesterase 5A2
- cGMP-binding cGMP-specific phosphodiesterase
- phosphodiesterase type 5
- cGMP-binding/cGMP-specific phosphodiesterase
- 3',5'-Cyclic GMP Phosphodiesterase
- phosphodiesterase 5A, cGMP-specific
- phosphodiesterase 5a, cGMP-specific
- phosphodiesterase 5a
- cGMP-specific 3',5'-cyclic phosphodiesterase-like
- cyclic nucleotide phosphodiesterase 5a
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