Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

PDE8B Produits

(phosphodiesterase 8B (PDE8B))

Catégories

The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories PDE8B en vedette

PDE8B Anticorps

High quality antibodies with extensive validation data.

PDE8B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB
Validations
  • (3)
  • (1)
N° du produit ABIN1881646
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Bat, Horse, Human, Monkey
Application IHC (p), IHC
Validations
  • (2)
N° du produit ABIN213535
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IF
Validations
  • (1)
N° du produit ABIN7155168
Quantité 100 μL
Fiche technique Fiche technique

PDE8B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3094523
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3131150
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PDE8B

Horvath, Faucz, Finkielstain, Nikita, Rothenbuhler, Almeida, Mericq, Stratakis: "Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels." dans: Thyroid : official journal of the American Thyroid Association, Vol. 20, Issue 4, pp. 363-7, (2010) (PubMed).

Shields, Freathy, Knight, Hill, Weedon, Frayling, Hattersley, Vaidya: "Phosphodiesterase 8B gene polymorphism is associated with subclinical hypothyroidism in pregnancy." dans: The Journal of clinical endocrinology and metabolism, Vol. 94, Issue 11, pp. 4608-12, (2009) (PubMed).

Bimpaki, Nesterova, Stratakis: "Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes." dans: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 1, pp. 153-61, (2009) (PubMed).

Horvath, Giatzakis, Tsang, Greene, Osorio, Boikos, Libè, Patronas, Robinson-White, Remmers, Bertherat, Nesterova, Stratakis: "A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex." dans: European journal of human genetics : EJHG, Vol. 16, Issue 10, pp. 1245-53, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à PDE8B

phosphodiesterase 8B (PDE8B), high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (LOC100468338), phosphodiesterase 8B (pde8b), phosphodiesterase 8B (Pde8b), ADSD, B230331L10Rik, C030047E14Rik, PDE8B, PPNAD3, RNPDE8B

Protein level used designations for PDE8B

  • phosphodiesterase 8B
  • high-affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
  • high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B-like
  • 3',5' cyclic nucleotide phosphodiesterase 8B
  • cell proliferation-inducing gene 22 protein
  • high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
  • hsPDE8B
  • cAMP-specific cyclic nucleotide phosphodiesterase PDE8
Vous êtes ici:
Support technique