PDK2 Produits
(Pyruvate Dehydrogenase Kinase, Isozyme 2 (PDK2))
Catégories
This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010].
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Catégories PDK2 en vedette
PDK2 Anticorps
High quality antibodies with extensive validation data.
PDK2 Kits ELISA
Reliable ELISA kits for a wide range of species.
PDK2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PDK2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), RNAi
Validations
- (4)
- (6)
N° du produit
ABIN562160
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
N° du produit
ABIN7439423
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (5)
N° du produit
ABIN5542665
Quantité
100 μL
Fiche technique
Fiche technique
PDK2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6959010
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6231784
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5658317
Quantité
96 tests
Fiche technique
Fiche technique
PDK2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314551
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314549
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
N° du produit
ABIN5509069
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PDK2
: "PDK2 induces cisplatin-resistance in lung adenocarcinoma via transcriptional regulation of CNNM3." dans: Journal of drug targeting, Vol. 27, Issue 4, pp. 460-465, (2019) (PubMed).: "Selective Phosphorylation Inhibitor of Delta Protein Kinase C-Pyruvate Dehydrogenase Kinase Protein-Protein Interactions: Application for Myocardial Injury in Vivo." dans: Journal of the American Chemical Society, Vol. 138, Issue 24, pp. 7626-35, (2018) (PubMed).
: "Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Protein-Protein Interaction Inhibitor Reveals a Non-catalytic Role for GAPDH Oligomerization in Cell Death." dans: The Journal of biological chemistry, Vol. 291, Issue 26, pp. 13608-21, (2016) (PubMed).
: "Increasing Pyruvate Dehydrogenase Flux as a Treatment for Diabetic Cardiomyopathy: A Combined 13C Hyperpolarized Magnetic Resonance and Echocardiography Study." dans: Diabetes, Vol. 64, Issue 8, pp. 2735-43, (2015) (PubMed).
: "Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation." dans: Journal of cell science, Vol. 128, Issue 13, pp. 2319-29, (2015) (PubMed).
: "Retinoic acid-related orphan receptor alpha reprograms glucose metabolism in glutamine-deficient hepatoma cells." dans: Hepatology (Baltimore, Md.), Vol. 61, Issue 3, pp. 953-64, (2015) (PubMed).
: "Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species." dans: The Journal of biological chemistry, Vol. 287, Issue 42, pp. 35153-60, (2012) (PubMed).
: "p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2." dans: Cancer research, Vol. 72, Issue 2, pp. 560-7, (2012) (PubMed).
: "Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPAR?-independent mechanisms." dans: European journal of cell biology, Vol. 90, Issue 8, pp. 657-64, (2011) (PubMed).
: "The relationship between human skeletal muscle pyruvate dehydrogenase phosphatase activity and muscle aerobic capacity." dans: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 111, Issue 2, pp. 427-34, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à PDK2
pyruvate dehydrogenase kinase 2 (PDK2), pyruvate dehydrogenase kinase, isoenzyme 2 (Pdk2), pyruvate dehydrogenase kinase 2 (Pdk2), pyruvate dehydrogenase kinase, isozyme 2b (pdk2b), PDHK2, Pdk, PDK2, PDKII, zgc:56209Protein level used designations for PDK2
- PDH kinase 2
- pyruvate dehydrogenase kinase, isoenzyme 2
- pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial
- [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2, mitochondrial
- pyruvate dehydrogenase 2
- pyruvate dehydrogenase kinase, isozyme 2
- PDK P45
- pyruvate dehydrogenase kinase 2 subunit p45 (PDK2)
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