Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

PDK3 Produits

(Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))

Catégories

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories PDK3 en vedette

PDK3 Anticorps

High quality antibodies with extensive validation data.

PDK3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PDK3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
  • (4)
N° du produit ABIN562161
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (2)
  • (2)
N° du produit ABIN391038
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS
Validations
  • (1)
  • (2)
N° du produit ABIN652286
Quantité 400 μL
Fiche technique Fiche technique

PDK3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6206626
Quantité 96 tests
Fiche technique Fiche technique

PDK3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314554
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314553
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7417198
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PDK3

Hou, Zhang, Han, Ge, Ma, Zhang, Moley, Schedl, Wang: "Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation." dans: Journal of cell science, Vol. 128, Issue 13, pp. 2319-29, (2015) (PubMed).

Ho, Coomber: "Pyruvate dehydrogenase kinase expression and metabolic changes following dichloroacetate exposure in anoxic human colorectal cancer cells." dans: Experimental cell research, Vol. 331, Issue 1, pp. 73-81, (2015) (PubMed).

Shimura, Nakai, Jiao, Osanai, Kashikura, Endo, Soga, Goda, Minamisawa: "Metabolomic profiling analysis reveals chamber-dependent metabolite patterns in the mouse heart." dans: American journal of physiology. Heart and circulatory physiology, Vol. 305, Issue 4, pp. H494-505, (2013) (PubMed).

Hwang, Wu, Harris: "Additive effects of clofibric acid and pyruvate dehydrogenase kinase isoenzyme 4 (PDK4) deficiency on hepatic steatosis in mice fed a high saturated fat diet." dans: The FEBS journal, Vol. 279, Issue 10, pp. 1883-93, (2012) (PubMed).

Halim, Mcfate, Mohyeldin, Okagaki, Korotchkina, Patel, Jeoung, Harris, Schell, Verma: "Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons." dans: Glia, Vol. 58, Issue 10, pp. 1168-76, (2010) (PubMed).

Jeoung, Harris: "Pyruvate dehydrogenase kinase-4 deficiency lowers blood glucose and improves glucose tolerance in diet-induced obese mice." dans: American journal of physiology. Endocrinology and metabolism, Vol. 295, Issue 1, pp. E46-54, (2008) (PubMed).

Lu, Lin, Chen, Lai, Tsai: "Induction of pyruvate dehydrogenase kinase-3 by hypoxia-inducible factor-1 promotes metabolic switch and drug resistance." dans: The Journal of biological chemistry, Vol. 283, Issue 42, pp. 28106-14, (2008) (PubMed).

McFate, Mohyeldin, Lu, Thakar, Henriques, Halim, Wu, Schell, Tsang, Teahan, Zhou, Califano, Jeoung, Harris, Verma: "Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells." dans: The Journal of biological chemistry, Vol. 283, Issue 33, pp. 22700-8, (2008) (PubMed).

Xu, Han, Epstein, Liu: "Regulation of PDK mRNA by high fatty acid and glucose in pancreatic islets." dans: Biochemical and biophysical research communications, Vol. 344, Issue 3, pp. 827-33, (2006) (PubMed).

Synonymes et noms alternatifs relatifs à PDK3

pyruvate dehydrogenase kinase 3 (PDK3), pyruvate dehydrogenase kinase 3 (Pdk3), pyruvate dehydrogenase kinase, isozyme 3a (pdk3a), pyruvate dehydrogenase kinase 3 (pdk3), pyruvate dehydrogenase kinase, isoenzyme 3 (Pdk3), fragile site, 5-azacytidine type, common, fra(1)(q12) (FRA1J), pyruvate dehydrogenase kinase, isozyme 3b (pdk3b), 2610001M10Rik, AI035637, pdk3, PDK3, zgc:158702

Protein level used designations for PDK3

  • pyruvate dehydrogenase kinase, isoenzyme 3
  • pyruvate dehydrogenase, lipoamide, kinase isozyme 3, mitochondrial
  • Pyruvate dehydrogenase kinase 3
  • [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial
  • pyruvate dehydrogenase kinase 3
  • pyruvate dehydrogenase kinase, isozyme 3
  • pyruvate dehydrogenase [lipoamide] kinase isozyme 3, mitochondrial-like
  • pyruvate dehydrogenase kinase, isozyme 3b
Vous êtes ici:
Support technique