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PDX1 Produits

(Pancreatic and Duodenal Homeobox 1 (PDX1))

Catégories

The protein encoded by this gene is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. The encoded nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4). [provided by RefSeq, Jul 2008].

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Catégories PDX1 en vedette

PDX1 Anticorps

High quality antibodies with extensive validation data.

PDX1 Kits ELISA

Reliable ELISA kits for a wide range of species.

PDX1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PDX1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7441508
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (2)
  • (4)
N° du produit ABIN969554
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (6)
N° du produit ABIN3032144
Quantité 0.4 mL
Fiche technique Fiche technique

PDX1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969131
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958375
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4884142
Quantité 96 tests
Fiche technique Fiche technique

PDX1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314593
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7409143
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7409140
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PDX1

Lam, Chatterjee, Shen, Cox, Kushner: "Low-Level Insulin Content Within Abundant Non-β Islet Endocrine Cells in Long-standing Type 1 Diabetes." dans: Diabetes, Vol. 68, Issue 3, pp. 598-608, (2019) (PubMed).

Ramdas, Sharma, Kaul, Bhatia: "Possible role of miR-2909 RNomics in arsenic mediated pancreatic β-cell dysfunction." dans: Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS), Vol. 50, pp. 263-267, (2019) (PubMed).

Wang, Liu, Liu, Chen, Hu, Hu, Yuan, Wu, Dai, Xu: "Sall2 knockdown exacerbates palmitic acid induced dysfunction and apoptosis of pancreatic NIT-1 beta cells." dans: Biomedicine & pharmacotherapy, Vol. 104, pp. 375-382, (2018) (PubMed).

Aguiar, Orechio, Fratini, Carreira, Castelucci, Miglino: "Isolation and Characterization of Pancreatic Canine Fetal Cells at the Final Stage of Gestation." dans: Anatomical record (Hoboken, N.J. : 2007), (2018) (PubMed).

Lam, Cox, Jacobson, Rankin, Kushner: "Highly Proliferative α-Cell-Related Islet Endocrine Cells in Human Pancreata." dans: Diabetes, Vol. 67, Issue 4, pp. 674-686, (2018) (PubMed).

Wang, Ren, Hu, Ma, Wang, Liang, Liu: "Effect of Wnt Signaling on the Differentiation of Islet β-Cells from Adipose-Derived Stem Cells." dans: BioMed research international, Vol. 2017, pp. 2501578, (2017) (PubMed).

Zheng, Zhai, Li, Ma, Zhu, Du, Li, Hua: "The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation." dans: Scientific reports, Vol. 6, pp. 37414, (2016) (PubMed).

Jian, Mao, Xu, Li, Wang, Luo, Zhou, He, Wang, Zhang: "Generation of insulin-producing cells from C3H10T1/2 mesenchymal progenitor cells." dans: Gene, Vol. 562, Issue 1, pp. 107-16, (2015) (PubMed).

Pondugala, Sasikala, Guduru, Rebala, Nageshwar Reddy: "Interferon-? Decreases Nuclear Localization of Pdx-1 and Triggers ?-Cell Dysfunction in Chronic Pancreatitis." dans: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 35, Issue 7, pp. 523-9, (2015) (PubMed).

Perelis, Marcheva, Ramsey, Schipma, Hutchison, Taguchi, Peek, Hong, Huang, Omura, Allred, Bradfield, Dinner, Barish, Bass: "Pancreatic β cell enhancers regulate rhythmic transcription of genes controlling insulin secretion." dans: Science (New York, N.Y.), Vol. 350, Issue 6261, pp. aac4250, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à PDX1

pancreatic and duodenal homeobox 1 (PDX1), pancreatic and duodenal homeobox 1 (pdx1), pancreatic and duodenal homeobox 1 (Pdx1), pancreatic and duodenal homeobox 1 S homeolog (pdx1.S), GSF, IDX-1, Idx1, IPF-1, IPF1, ipf1, Ipf1, IUF1, MODY4, Mody4, PDX-1, pdx-1, PDX1, STF-1, Stf1, XlHbox-8, xlhbox8, zgc:100874

Protein level used designations for PDX1

  • IPF-1
  • IUF-1
  • glucose-sensitive factor
  • insulin promoter factor 1, homeodomain transcription factor
  • insulin upstream factor 1
  • islet/duodenum homeobox-1
  • pancreas/duodenum homeobox protein 1
  • pancreatic-duodenal homeobox factor 1
  • somatostatin transcription factor 1
  • somatostatin-transactivating factor 1
  • homeodomain protein PDX-1
  • pancreatic and duodenum homeobox 1
  • pancreatic duodenal homeobox gene 1
  • pancreatic and duodenal homeobox 1
  • islet/duodenum homeobox 1
  • pancreatic and duodenal homeobox gene 1
  • IDX-1
  • Insulin promoter factor 1
  • STF-1
  • insulin promotor factor 1
  • somatostatin transactivating factor 1
  • homeodomain protein PDX1
  • Homeobox protein 8
  • XlHbox 8 protein
  • LOW QUALITY PROTEIN: pancreas/duodenum homeobox protein 1
  • Homeodomain protein PDX1
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