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PDZK1 Produits

(PDZ Domain Containing 1 (PDZK1))
This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].

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Catégories PDZK1 en vedette

PDZK1 Anticorps

High quality antibodies with extensive validation data.

PDZK1 Kits ELISA

Reliable ELISA kits for a wide range of species.

PDZK1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PDZK1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN562170
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (3)
N° du produit ABIN7269199
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN518773
Quantité 200 μL
Fiche technique Fiche technique

PDZK1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1144046
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1144047
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1144049
Quantité 96 tests
Fiche technique Fiche technique

PDZK1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1314614
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN5852951
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN2131092
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PDZK1

Jansson, Venugopal, Sánchez, Magenheimer, Reif, Wallace, Calvet, Blanco: "Ouabain Regulates CFTR-Mediated Anion Secretion and Na,K-ATPase Transport in ADPKD Cells." dans: The Journal of membrane biology, Vol. 248, Issue 6, pp. 1145-57, (2016) (PubMed).

Fry, Su, Yiu, Cuthbert, Trachtman, Karet Frankl: "Mutation conferring apical-targeting motif on AE1 exchanger causes autosomal dominant distal RTA." dans: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 7, pp. 1238-49, (2012) (PubMed).

James, Brulhart-Meynet, Singh, Riederer, Seidler, Out, Van Berkel, Deakin: "The scavenger receptor class B, type I is a primary determinant of paraoxonase-1 association with high-density lipoproteins." dans: Arteriosclerosis, thrombosis, and vascular biology, Vol. 30, Issue 11, pp. 2121-7, (2010) (PubMed).

Robichaud, Francis, Vance: "A role for hepatic scavenger receptor class B, type I in decreasing high density lipoprotein levels in mice that lack phosphatidylethanolamine N-methyltransferase." dans: The Journal of biological chemistry, Vol. 283, Issue 51, pp. 35496-506, (2008) (PubMed).

Hashimoto, Suzuki, Taniguchi, Noguchi, Yohda, Odaka: "Catalytic mechanism of nitrile hydratase proposed by time-resolved X-ray crystallography using a novel substrate, tert-butylisonitrile." dans: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36617-23, (2008) (PubMed).

Walker, MacLeod, Williams, Cameron, Smyth, Langdon: "Estrogen-regulated gene expression predicts response to endocrine therapy in patients with ovarian cancer." dans: Gynecologic oncology, Vol. 106, Issue 3, pp. 461-8, (2007) (PubMed).

Lan, Silver: "Fenofibrate induces a novel degradation pathway for scavenger receptor B-I independent of PDZK1." dans: The Journal of biological chemistry, Vol. 280, Issue 24, pp. 23390-6, (2005) (PubMed).

Wang, Wang, Xiao, Murray, Novikoff, Angeletti, Orr, Lan, Silver, Wolkoff: "Interaction with PDZK1 is required for expression of organic anion transporting protein 1A1 on the hepatocyte surface." dans: The Journal of biological chemistry, Vol. 280, Issue 34, pp. 30143-9, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à PDZK1

PDZ domain containing 1 (PDZK1), PDZ domain containing 1 L homeolog (pdzk1.L), PDZ domain containing 1 (pdzk1), PDZ domain containing 1 (Pdzk1), 1700023D20Rik, 2610507N21Rik, 4921513F16Rik, AI267131, AI314638, AL022680, CAP70, CLAMP, Clamp, D3Ertd537e, mPDZK1, NHERF-3, NHERF3, PDZD1, Pdzd1, PDZK1, xpdzk1

Protein level used designations for PDZK1

  • PDZ domain containing 1
  • Na(+)/H(+) exchange regulatory cofactor NHE-RF3-like
  • CFTR-associated protein of 70 kDa
  • Na(+)/H(+) exchange regulatory cofactor NHE-RF3
  • PDZ-containing kidney protein 1
  • na/Pi cotransporter C-terminal-associated protein 1
  • naPi-Cap1
  • sodium-hydrogen exchanger regulatory factor 3
  • NHERF-3
  • Na(+)/H(+) exchanger regulatory factor 3
  • PDZ domain-containing protein 1
  • PDZK1-like protein
  • C-terminal linking and modulating protein
  • C-terminal-linking and modulating protein
  • dietary Pi-regulated RNA-1
  • diphor-1
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