PEG10 Produits
(Paternally Expressed 10 (PEG10))
Catégories
This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas. [provided by RefSeq, May 2010].
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Catégories PEG10 en vedette
PEG10 Anticorps
High quality antibodies with extensive validation data.
PEG10 Kits ELISA
Reliable ELISA kits for a wide range of species.
PEG10 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PEG10 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC
Validations
- (6)
N° du produit
ABIN1681320
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, ICC
Validations
- (3)
- (3)
N° du produit
ABIN969348
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (3)
N° du produit
ABIN524962
Quantité
50 μg
Fiche technique
Fiche technique
PEG10 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969163
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6225627
Quantité
96 tests
Fiche technique
Fiche technique
PEG10 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314640
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3094526
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3135926
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits PEG10
: "ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis." dans: Nature medicine, Vol. 24, Issue 12, pp. 1887-1898, (2019) (PubMed).: "DREAM and RB cooperate to induce gene repression and cell-cycle arrest in response to p53 activation." dans: Nucleic acids research, Vol. 47, Issue 17, pp. 9087-9103, (2019) (PubMed).
: "PEG10 overexpression induced by E2F-1 promotes cell proliferation, migration, and invasion in pancreatic cancer." dans: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 30, (2017) (PubMed).
: "miR-122-mediated translational repression of PEG10 and its suppression in human hepatocellular carcinoma." dans: Journal of translational medicine, Vol. 14, Issue 1, pp. 200, (2016) (PubMed).
: "uORFs, reinitiation and alternative translation start sites in human mRNAs." dans: FEBS letters, Vol. 582, Issue 9, pp. 1293-7, (2008) (PubMed).
: "PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma." dans: FEBS letters, Vol. 582, Issue 18, pp. 2793-8, (2008) (PubMed).
: "Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells." dans: Oncogene, Vol. 26, Issue 39, pp. 5741-51, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à PEG10
paternally expressed 10 (PEG10), paternally expressed 10 (Peg10), AA407948, EDR, Edr, HB-1, Mar2, Mart2, MEF3L, MyEF-3, RGAG3Protein level used designations for PEG10
- MEF3 like 1
- MEF3-like protein 1
- embryonal carcinoma differentiation regulated
- embryonal carcinoma differentiation-regulated protein
- mammalian retrotransposon-derived protein 2
- myelin expression factor 3-like protein 1
- paternally expressed gene 10 protein
- retrotransposon gag domain containing 3
- retrotransposon gag domain-containing protein 3
- retrotransposon-derived gag-like polyprotein
- retrotransposon-derived protein PEG10
- ty3/Gypsy-like protein
- MyEF-3 like
- embryonal carcinoma differentiation regulated protein
- myelin expression factor 3
- paternally expressed 10
- LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10
- retrotransposon-derived protein PEG10-like
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