Caspase Recruitment Domain Family, Member 11 (CARD11) (Middle Region) Peptide
CARD11
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits CARD11
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- SPRLSRASFL FGQLLQFVSR SENKYKRMNS NERVRIISGS PLGSLARSSL
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CARD11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Caspase Recruitment Domain Family, Member 11 (CARD11) peptide
CARD11 Reactivité: Humain, Souris, Boeuf (Vache), Chien Hôte: Synthetic BP, Imm
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
- Synonymes
- BENTA Peptide, BIMP3 Peptide, CARMA1 Peptide, PPBL Peptide, 0610008L17Rik Peptide, 2410011D02Rik Peptide, CARD11 Peptide, LOC100232755 Peptide, caspase recruitment domain family member 11 Peptide, caspase recruitment domain family, member 11 Peptide, caspase recruitment domain-containing protein 11 Peptide, CARD11 Peptide, Card11 Peptide, LOC100550812 Peptide, card11 Peptide
- Sujet
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The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
Alias Symbols: PPBL, BENTA, BIMP3, IMD11, CARMA1
Protein Size: 1171 - ID gène
- 84433
- NCBI Accession
- NM_032415, NP_115791
- UniProt
- Q8TES3
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