VPS72
(Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-VPS72 antibody (Catalog #: ARP74345_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
VPS72
Reactivité: Humain, Souris, Boeuf (Vache)
Hôte: Synthetic
BP
Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
VPS72
(Vacuolar Protein Sorting 72 Homolog (S. Cerevisiae) (VPS72))
Synonymes
CG4621 Peptide, Dmel\\CG4621 Peptide, dYL-1 Peptide, vps72 Peptide, MGC82727 Peptide, Vps72 Peptide, YL-1 Peptide, ACYPI009531 Peptide, Tcfl1 Peptide, CFL1 Peptide, Swc2 Peptide, TCFL1 Peptide, YL1 Peptide, si:dkeyp-24a7.1 Peptide, CG4621 gene product from transcript CG4621-RB Peptide, vacuolar protein sorting 72 homolog L homeolog Peptide, potential vacuolar protein sorting protein Peptide, vacuolar protein sorting 72 homolog Peptide, vacuolar protein sorting-associated protein 72 homolog Peptide, vacuolar protein sorting 72 Peptide, vacuolar protein sorting 72 homolog S homeolog Peptide, vacuolar protein sorting 72 homolog (S. cerevisiae) Peptide, YL-1 Peptide, vps72.L Peptide, VPS72 Peptide, Vps72 Peptide, vps72.S Peptide, vps72 Peptide
Sujet
The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.