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Homeobox Protein Nkx-2.4 (LOC105228315) Peptide

LOC105228315 Reactivité: Humain Hôte: Synthetic WB
N° du produit ABIN5671334
  • Antigène
    NKX21 (LOC105228315) (Homeobox Protein Nkx-2.4 (LOC105228315))
    Origine
    Humain
    Source
    Synthetic
    Application
    Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-NKX21 antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    NKX21 (LOC105228315) (Homeobox Protein Nkx-2.4 (LOC105228315))
    Sujet
    This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.

    Alias Symbols: NKX2A, TITF1, TTF1

    Protein Size: 371
    Poids moléculaire
    40 kDa
    ID gène
    7080
    NCBI Accession
    NP_003308
    UniProt
    P43699
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