A synthetic peptide for use as a blocking control in assays to test for specificity of SIGLEC10 antibody, Alternative Names: SIGLEC10 control peptide, SIGLEC10 antibody Blocking Peptide, Anti-SIGLEC10 Blocking Peptide, Sialic Acid Binding Ig-Like Lectin 10 Blocking Peptide, MGC126774 Blocking Peptide, PRO940 Blocking Peptide, SIGLEC-10 Blocking Peptide, SLG2 Blocking Peptide, SIGLEC10, SIGLEC-10, SIGLEC 10, SIGLEC-10 Blocking Peptide, SIGLEC 10 Blocking Peptide
SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. SIGLEC10 preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, SIGLEC10 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.