A synthetic peptide for use as a blocking control in assays to test for specificity of ATG5 antibody, Alternative Names: ATG5 control peptide, ATG5 antibody Blocking Peptide, Anti-ATG5 Blocking Peptide, Atg5 Autophagy Related 5 Homolog Blocking Peptide, APG5 Blocking Peptide, APG5L Blocking Peptide, ASP Blocking Peptide, hAPG5 Blocking Peptide, ATG5, ATG-5, ATG 5, ATG-5 Blocking Peptide, ATG 5 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
ATG5
(ATG5 Autophagy Related 5 (ATG5))
Synonymes
APG5 Peptide, APG5-LIKE Peptide, APG5L Peptide, ASP Peptide, hAPG5 Peptide, ATG5 Peptide, CG1643 Peptide, DmAtg5 Peptide, Dmel\\CG1643 Peptide, atg5 Peptide, 2010107M05Rik Peptide, 3110067M24Rik Peptide, AW319544 Peptide, Apg5l Peptide, Atg5l Peptide, C88337 Peptide, Paddy Peptide, apg5l Peptide, zgc:100934 Peptide, ATATG5 Peptide, AUTOPHAGY 5 Peptide, MKP11.20 Peptide, MKP11_20 Peptide, autophagy related 5 Peptide, Autophagy-related 5 Peptide, ATG5 autophagy related 5 homolog (S. cerevisiae) Peptide, autophagy related 5 L homeolog Peptide, similar to S. cerevisiae ATG5 (YPL149W) which nucleates preautophagosome formation as a conjugate with Atg12 Peptide, autophagy protein Apg5 family Peptide, ATG5 Peptide, Atg5 Peptide, atg5 Peptide, atg5.L Peptide, APG5 Peptide
Sujet
ATG5 is required for autophagy. It conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 may play an important role in the apoptotic process, possibly within the modified cytoskeleton. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity.