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Transmembrane Protein 173 (TMEM173) Peptide

TMEM173 Reactivité: Mammifères Hôte: Synthetic BP, WB, IHC
N° du produit ABIN937495
  • Antigène Tous les produits STING/TMEM173 (TMEM173)
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    Type de proteíne
    Synthetic
    Origine
    Mammifères
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    DPNIRFLDKL PQQTGDHAGI KDRVYSNSIY ELLENGQRAG TCVLEYATPL
    Attributs du produit
    A synthetic peptide for use as a blocking control in assays to test for specificity of TMEM173 antibody,
    Alternative Names: TMEM173 control peptide, TMEM173 antibody Blocking Peptide, Anti-TMEM173 Blocking Peptide, Transmembrane Protein 173 Blocking Peptide, FLJ38577 Blocking Peptide, TMEM173, TMEM-173, TMEM 173, TMEM-173 Blocking Peptide, TMEM 173 Blocking Peptide
  • Indications d'application
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    Store at -20 °C long term.
  • Antigène
    STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
    Synonymes
    ERIS Peptide, MITA Peptide, MPYS Peptide, NET23 Peptide, STING Peptide, 2610307O08Rik Peptide, Mita Peptide, RGD1562552 Peptide, transmembrane protein 173 Peptide, TMEM173 Peptide, Tmem173 Peptide
    Sujet
    TMEM173 acts as a facilitator of innate immune signaling. It is able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon (IFN-alpha and IFN-beta) and exert a potent anti-viral state following expression. TMEM173 may be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons.It also may be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). TMEM173 mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
    Poids moléculaire
    42 kDa
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