A synthetic peptide for use as a blocking control in assays to test for specificity of KHDRBS2 antibody, Alternative Names: KHDRBS2 control peptide, KHDRBS2 antibody Blocking Peptide, Anti-KHDRBS2 Blocking Peptide, KH domain containing, RNA binding, signal transduction associated 2 Blocking Peptide, FLJ38664 Blocking Peptide, MGC26664 Blocking Peptide, SLM-1 Blocking Peptide, SLM1 Blocking Peptide, bA535F17.1 Blocking Peptide, KHDRBS2, KHDRBS-2, KHDRBS 2, KHDRBS-2 Blocking Peptide, KHDRBS 2 Blocking Peptide
KHDRBS2 is a RNA-binding protein that plays a role in the regulation of alternative splicing and influences mRNA splice site selection and exon inclusion. Its phosphorylation by FYN inhibits its ability to regulate splice site selection. KHDRBS2 induces an increased concentration-dependent incorporation of exon in CD44 pre-mRNA by direct binding to purine-rich exonic enhancer. KHDRBS2 may function as an adapter protein for Src kinases during mitosis. KHDRBS2 binds both poly(A) and poly(U) homopolymers. Phosphorylation by PTK6 inhibits its RNA-binding ability.