A synthetic peptide for use as a blocking control in assays to test for specificity of CENPH antibody, Alternative Names: CENPH control peptide, CENPH antibody Blocking Peptide, Anti-CENPH Blocking Peptide, Centromere Protein H Blocking Peptide, NNF1 Blocking Peptide, PMF1 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
CENPH
(Centromere Protein H (CENPH))
Synonymes
1700021I11Rik Peptide, 2410018A12Rik Peptide, 2610042E16Rik Peptide, 2810046K12Rik Peptide, AU044255 Peptide, CENP-H Peptide, ENP Peptide, si:dkey-186m8.3 Peptide, cenp-h Peptide, centromere protein H Peptide, centromere protein H pseudogene Peptide, CENPH Peptide, Cenph Peptide, cenph Peptide, LOC100356112 Peptide, LOC101788801 Peptide
Sujet
Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. CENPH colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex.