A synthetic peptide for use as a blocking control in assays to test for specificity of MBP antibody, Alternative Names: MBP control peptide, MBP antibody Blocking Peptide, Anti-MBP Blocking Peptide, Myelin Basic Protein Blocking Peptide, MGC99675 Blocking Peptide
MBP
Reactivité: Humain
Hôte: Synthetic
WB, BP, IHC, IP
Indications d'application
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
MBP
(Myelin Basic Protein (MBP))
Synonymes
C76307 Peptide, Hmbpr Peptide, R75289 Peptide, golli-mbp Peptide, mld Peptide, shi Peptide, Mbps Peptide, cb274 Peptide, fj33b11 Peptide, mbp Peptide, wu:fj33b11 Peptide, wu:fq15b02 Peptide, zgc:136630 Peptide, MGC115135 Peptide, myelin basic protein Peptide, myelin basic protein a Peptide, myelin basic protein L homeolog Peptide, MBP Peptide, Mbp Peptide, mbpa Peptide, mbp Peptide, mbp.L Peptide
Sujet
The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells.