PTPN11
Reactivité: Humain, Souris
Hôte: Synthetic
BP, BI
Indications d'application
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
PTPN11
(Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
Synonymes
BPTP3 Peptide, CFC Peptide, NS1 Peptide, PTP-1D Peptide, PTP2C Peptide, SH-PTP2 Peptide, SH-PTP3 Peptide, SHP2 Peptide, 2700084A17Rik Peptide, AW536184 Peptide, PTP1D Peptide, SAP-2 Peptide, SHP-2 Peptide, Shp2 Peptide, Syp Peptide, SYP Peptide, bptp3 Peptide, cfc Peptide, ns1 Peptide, ptp-2 Peptide, ptp2c Peptide, ptpn11 Peptide, ptpn11-a Peptide, ptpn11-b Peptide, shp-2 Peptide, shp2 Peptide, fa14b09 Peptide, wu:fa14b09 Peptide, wu:fi24f03 Peptide, zgc:55388 Peptide, zgc:63553 Peptide, protein tyrosine phosphatase, non-receptor type 11 Peptide, protein tyrosine phosphatase, non-receptor type 11 S homeolog Peptide, protein tyrosine phosphatase, non-receptor type 11, a Peptide, protein tyrosine phosphatase, non-receptor type 11, b Peptide, PTPN11 Peptide, Ptpn11 Peptide, ptpn11.S Peptide, ptpn11a Peptide, ptpn11b Peptide
Classe de substances
Viral Protein
Sujet
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration.