A synthetic peptide for use as a blocking control in assays to test for specificity of KEAP1 antibody, Alternative Names: KEAP1 control peptide, KEAP1 antibody Blocking Peptide, Anti-KEAP1 Blocking Peptide, kelch-like ECH-associated protein 1 Blocking Peptide, KEAP1, KEAP-1, KEAP 1, KEAP-1 Blocking Peptide, KEAP 1 Blocking Peptide
KEAP1
Reactivité: Humain, Souris
Hôte: Synthetic
BP, BI
Indications d'application
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
KEAP1
(Kelch-Like ECH-Associated Protein 1 (KEAP1))
Synonymes
INrf2 Peptide, KLHL19 Peptide, INRF2 Peptide, mKIAA0132 Peptide, Inrf2 Peptide, fb36f11 Peptide, keap1 Peptide, wu:fb36f11 Peptide, KEAP1 Peptide, klhl19 Peptide, zgc:171654 Peptide, kelch like ECH associated protein 1 Peptide, kelch-like ECH-associated protein 1 Peptide, Kelch-like ECH-associated protein 1 Peptide, kelch-like ECH-associated protein 1a Peptide, kelch like ECH associated protein 1 L homeolog Peptide, kelch-like ECH-associated protein 1b Peptide, KEAP1 Peptide, Keap1 Peptide, keap1a Peptide, keap1 Peptide, keap1.L Peptide, keap1b Peptide
Sujet
KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.