A synthetic peptide for use as a blocking control in assays to test for specificity of GTSE1 antibody, Alternative Names: GTSE1 control peptide, GTSE1 antibody Blocking Peptide, Anti-GTSE1 Blocking Peptide, G-2 And S-Phase Expressed 1 Blocking Peptide, B99 Blocking Peptide, GTSE1, GTSE-1, GTSE 1, GTSE-1 Blocking Peptide, GTSE 1 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
GTSE1
(G-2 and S-Phase Expressed 1 (GTSE1))
Synonymes
gtse1 Peptide, MGC81588 Peptide, MGC89498 Peptide, GTSE1 Peptide, fb70b04 Peptide, fj88g09 Peptide, wu:fb70b04 Peptide, wu:fj88g09 Peptide, wu:fy65d12 Peptide, MGC114722 Peptide, B99 Peptide, Gtse-1 Peptide, RGD1563164 Peptide, G2 and S-phase expressed 1 S homeolog Peptide, G2 and S-phase expressed 1 Peptide, G-2 and S-phase expressed 1 Peptide, G2 and S-phase expressed 1 L homeolog Peptide, G two S phase expressed protein 1 Peptide, gtse1.S Peptide, gtse1 Peptide, GTSE1 Peptide, gtse1.L Peptide, Gtse1 Peptide
Sujet
GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis.