A synthetic peptide for use as a blocking control in assays to test for specificity of AUH antibody, Alternative Names: AUH control peptide, AUH antibody Blocking Peptide, Anti-AUH Blocking Peptide, Au Rna Binding Protein/Enoyl-Coenzyme A Hydratase Blocking Peptide
C77140 Peptide, W91705 Peptide, wu:fb81b10 Peptide, zgc:101057 Peptide, AU RNA binding methylglutaconyl-CoA hydratase Peptide, AU RNA binding protein/enoyl-coenzyme A hydratase Peptide, AU RNA binding protein/enoyl-CoA hydratase Peptide, AU RNA binding protein/enoyl-CoA hydratase S homeolog Peptide, AUH Peptide, Auh Peptide, auh Peptide, auh.S Peptide
Sujet
AU-specific RNA-binding enoyl-CoA hydratase (AUH) protein binds to the AU-rich element (ARE), a common element found in the 3' UTR of rapidly decaying mRNA such as c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. AUH is also homologous to enol-CoA hydratase, an enzyme involved in fatty acid degradation, and has been shown to have intrinsic hydratase enzymatic activity. AUH is thus a bifunctional chimera between RNA binding and metabolic enzyme activity.