A synthetic peptide for use as a blocking control in assays to test for specificity of AKR1 C2 antibody, Alternative Names: AKR1C2 control peptide, AKR1C2 antibody Blocking Peptide, Anti-AKR1C2 Blocking Peptide, Aldo-Keto Reductase Family 1 Member C2 Blocking Peptide, Dihydrodiol Dehydrogenase 2 Blocking Peptide, Bile Acid Binding protein Blocking Peptide, 3-alpha hydroxysteroid dehydrogenase type III Blocking Peptide, AKR1C-pseudo Blocking Peptide, BABP Blocking Peptide, DD Blocking Peptide, DD2 Blocking Peptide, DDH2 Blocking Peptide, HAKRD Blocking Peptide, HBAB Blocking Peptide, MCDR2 Blocking Peptide
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
AKR1C2
(Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
Synonymes
AKR1C-pseudo Peptide, BABP Peptide, DD Peptide, DD2 Peptide, DDH2 Peptide, HAKRD Peptide, HBAB Peptide, MCDR2 Peptide, SRXY8 Peptide, Akr1c21 Peptide, aldo-keto reductase family 1 member C2 Peptide, aldo-keto reductase family 1, member C2 Peptide, AKR1C2 Peptide, Akr1c2 Peptide
Sujet
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.