A synthetic peptide for use as a blocking control in assays to test for specificity of MICA antibody, Alternative Names: MICA control peptide, MICA antibody Blocking Peptide, Anti-MICA Blocking Peptide, Mhc Class I Polypeptide-Related Sequence A Blocking Peptide, MGC111087 Blocking Peptide, PERB11.1 Blocking Peptide
Purification
The antibody is affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide is removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
MICA
(MHC Class I Polypeptide-Related Sequence A (MICA))
Synonymes
MIC-A Peptide, PERB11.1 Peptide, MHC class I polypeptide-related sequence A Peptide, MICA Peptide
Sujet
MICA is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognised by intestinal epithelial gamma delta T cells.