This is a synthetic peptide designed for use in combination with anti-AKR1C2 Antibody(ARP53507_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
AKR1C2
(Aldo-keto Reductase Family 1, Member C2 (AKR1C2))
Synonymes
AKR1C-pseudo Peptide, BABP Peptide, DD Peptide, DD2 Peptide, DDH2 Peptide, HAKRD Peptide, HBAB Peptide, MCDR2 Peptide, SRXY8 Peptide, Akr1c21 Peptide, aldo-keto reductase family 1 member C2 Peptide, aldo-keto reductase family 1, member C2 Peptide, AKR1C2 Peptide, Akr1c2 Peptide
Sujet
This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.