This is a synthetic peptide designed for use in combination with anti-EIF2AK2 Antibody(ARP36709_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
EIF2AK2 might play a role in ER stress-induced apoptosis and in Alzheimer's disease. Alzheimer cases show prominent EIF2AK2 activation in association with neuritic plaques and pyramidal neurons in the hippocampus and neocortex.
Alias Symbols: EIF2AK1, MGC126524, PKR, PRKR
Protein Interaction Partner: EIF2S1,HIV2gp5,HTT,PRKRA,tat,CASP3,CASP7,CASP8,CDC42,CHUK,DNAJC3,EIF2AK2,EIF2S1,ELF2,HSP90AA1,HSPA1A,IKBKB,ILF3,JAK1,MAP3K5,MAP3K7,METAP2,NFKBIA,NPM1,PDGFRB,PPP1CA,PPP1CC,PPP2R5A,PRKRA,PRKRIP1,PRKRIR,PTGES3,RAC1,STAT1,STAT3,STRBP,TAB2,TARBP2,TIRAP,TP53,TY