GABRB3
(gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
Protein Region
Middle Region
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-GABRB3 antibody (Catalog #: ARP35339_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
GABRB3
(gamma-aminobutyric Acid (GABA) A Receptor, beta 3 (GABRB3))
Synonymes
GABRB3 Peptide, eca5 Peptide, LOC100230475 Peptide, ECA5 Peptide, A230092K12Rik Peptide, AW049585 Peptide, Cp1 Peptide, Gabrb-3 Peptide, beta3 Peptide, gamma-aminobutyric acid type A receptor beta3 subunit Peptide, gamma-aminobutyric acid (GABA) A receptor, beta 3 Peptide, gamma-aminobutyric acid type A receptor beta 3 subunit Peptide, gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 Peptide, GABRB3 Peptide, gabrb3 Peptide, Gabrb3 Peptide
Sujet
GABRB3 is a member of the ligand-gated ionic channel family. GABRB3 is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism.This gene encodes a member of the ligand-gated ionic channel family. The encoded protein is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. This gene is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in this gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism. Alternatively spliced transcript variants encoding isoforms with distinct signal peptides have been described.
Alias Symbols: MGC9051, ECA5
Protein Interaction Partner: AKAP5,ARFGEF2,GNB2L1,PPP2CA,AKAP5,PRKACA,PRKCA,UBC