GADD45B
(Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-GADD45B antibody (Catalog #: ARP48346_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
GADD45B
Reactivité: Humain, Singe, Souris, Rat
Hôte: Synthetic
BP, WB, ICo, IDe
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
GADD45B
(Growth Arrest and DNA-Damage-Inducible, beta (GADD45B))
Synonymes
GADD45BETA Peptide, MYD118 Peptide, AI323528 Peptide, Myd118 Peptide, CS131 Peptide, cb196 Peptide, gadd45b Peptide, gadd45b2 Peptide, sb:cb196 Peptide, zgc:73104 Peptide, gadd45beta Peptide, wu:fa92d10 Peptide, wu:fa98h12 Peptide, wu:fk65h03 Peptide, zgc:111973 Peptide, gadd45b1 Peptide, gadd45bl Peptide, zgc:112453 Peptide, growth arrest and DNA damage inducible beta Peptide, growth arrest and DNA-damage-inducible 45 beta Peptide, growth arrest and DNA-damage-inducible, beta Peptide, growth arrest and DNA-damage-inducible, beta a Peptide, growth arrest and DNA-damage-inducible, beta b Peptide, GADD45B Peptide, Gadd45b Peptide, gadd45ba Peptide, gadd45bb Peptide
Sujet
The function of GADD45B is involved in the regulation of growth and apoptosis.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZP566B133, GADD45BETA, MYD118
Protein Interaction Partner: EGR1,CCNB1,CDK1,GADD45GIP1,PCNA,PCNA,CCNB1,CDK1,CDKN1A,ESR1,GADD45G,GADD45GIP1,MAP2K7,MAP3K4,MAP3K5,PCNA,PPARA,PPARD,PPARG,CCNB1,CDK1,GADD45A,GADD45GIP1,MAP2K7,MAP3K4,MAP3K5