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Glutathione S-Transferase alpha 3 (GSTA3) (Middle Region) Peptide

GSTA3 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN977726
  • Antigène Tous les produits GSTA3
    GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    SSLISNFPLL KALKTRISNL PTVKKFLQPG SPRKPPADAK ALEEARKIFR
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-GSTA3 Antibody(ARP48484_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    GSTA3 (Glutathione S-Transferase alpha 3 (GSTA3))
    Synonymes
    GSTA3 Peptide, GST Peptide, GSTA1 Peptide, GSTA3-3 Peptide, GTA3 Peptide, GSTA2 Peptide, Gst2-3 Peptide, Yc2 Peptide, glutathione S-transferase alpha 3 Peptide, glutathione S-transferase A2 Peptide, glutathione S-transferase Peptide, glutathione S-transferase, alpha 3 Peptide, glutathione S-transferase Yc Peptide, GSTA3 Peptide, LOC474938 Peptide, gsta3 Peptide, Gsta3 Peptide, LOC100328911 Peptide
    Sujet
    Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. The enzyme encoded by this gene catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones. An additional transcript variant has been identified, but its full length sequence has not been determined.

    Alias Symbols: GSTA3-3, GTA3, MGC22232

    Protein Size: 222
    Poids moléculaire
    25 kDa
    ID gène
    2940
    NCBI Accession
    NM_000847, NP_000838
    UniProt
    Q16772
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