This is a synthetic peptide designed for use in combination with anti-HERC4 antibody (Catalog #: ARP42990_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
HERC4
(Hect Domain and RLD 4 (HERC4))
Synonymes
1700056O17Rik Peptide, 4921531D01Rik Peptide, 9530080M15Rik Peptide, mKIAA1593 Peptide, HECT and RLD domain containing E3 ubiquitin protein ligase 4 Peptide, HECT and RLD domain containing E3 ubiquitin protein ligase 4 S homeolog Peptide, hect domain and RLD 4 Peptide, HERC4 Peptide, herc4 Peptide, herc4.S Peptide, Herc4 Peptide
Sujet
HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins.