This is a synthetic peptide designed for use in combination with anti-HSPA4 antibody (Catalog #: ARP46073_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
HSPA4
(Heat Shock 70kDa Protein 4 (HSPA4))
Synonymes
APG-2 Peptide, HS24/P52 Peptide, HSPH2 Peptide, RY Peptide, hsp70 Peptide, hsp70RY Peptide, Hsp110 Peptide, Hsp70 Peptide, irp94 Peptide, 70kDa Peptide, AI317151 Peptide, Hsp70RY Peptide, mKIAA4025 Peptide, hspa4 Peptide, wu:fi30e11 Peptide, zgc:55743 Peptide, zgc:77413 Peptide, hs24/p52 Peptide, hspa4-a Peptide, osp94 Peptide, pg-2 Peptide, hspa4l Peptide, wu:fc41d05 Peptide, wu:fi59h02 Peptide, wu:fj35c08 Peptide, zgc:55506 Peptide, heat shock protein family A (Hsp70) member 4 Peptide, heat shock protein family A member 4 Peptide, heat shock protein 4 Peptide, heat shock protein 4b Peptide, heat shock protein family A (Hsp70) member 4 S homeolog Peptide, heat shock protein 4a Peptide, HSPA4 Peptide, Hspa4 Peptide, hspa4b Peptide, hspa4.S Peptide, hspa4a Peptide
Sujet
HSPA4(Hsp70) belongs to the heat shock protein 70 family. It was isolated as a putative Rictor interacting protein and interaction with membranes acts as a platform for its release into the extracellular environment during its recovery from stress. Hsp70 gene expression in Rheumatoid Arthitis-affected synovial tissue is followed by Hsp70 cell surface expression on fibroblast-like synovial cells growing from RA synovial tissue. Serum Hsp70 levels were increased in Systemic sclerosis patients, and associated with pulmonary fibrosis, skin sclerosis, renal vascular damage, oxidative stress, and inflammation.
Alias Symbols: APG-2, HS24/P52, MGC131852, RY, hsp70, hsp70RY, HSPH2
Protein Interaction Partner: KPNA2,BRMS1,CD40,CDC73,DDIT4,DUSP1,ESR1,GATA1,GRPEL2,HDAC3,IKBKG,KPNA2,NR3C2,OLR1,PHLDA1,PPP1CA,PRSS23,RAF1,SMAD3,STUB1,TRAF6,APAF1,BAG1,BAG1,BAG4,BAG5,BCOR,Bmi1,CDC73,CDK1,CHTF18,Cbx2,DNAJB1,DNAJB11,DNAJC3,DNMBP,ESR1,FES,GUCY1A2,H2AFY,HCFC1,HDAC1,HDAC2,HDAC3,HNRNPD,HSBP1,HSF1,HSPBP1,HTT,IRS4,ISG15,KRT18,LIMK1,MAP3K3,MARK4,NCOR1,NQO1,P2rx7,PARK2,PCGF1,PRKCB,PRSS23,SELS,SGTA,SSE1,STIP1,STUB1,TCERG1,TIMM44,TP53,TTC1,UBC,ZMYM2