This is a synthetic peptide designed for use in combination with anti-INSR antibody (Catalog #: ARP41374_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream media
Alias Symbols: CD220, HHF5
Protein Interaction Partner: HMGA1,CSK,GRB10,IRS1,IRS1,IRS2,JAK1,PIK3R1,PIK3R1,SHC1,SOCS1,SOCS6,ACP1,ADRB2,AHSG,ARF1,ARHGAP26,CALM1,CALM3,CALM3,CAV1,CAV3,CBL,CEACAM1,CRK,CRKL,CSK,DOK1,DOK4,DOK5,ENPP1,FABP4,FRS2,GAB1,GNB2L1,GRB10,GRB14,GRB7,HRAS,IGF1R,IGF2,INS,INSR,INSRR,IRS1,IRS2,JAK1,JAK2,KHDRBS1,KRT27,MAD2L1,MAPK3,PIK3R1,PIK3R3,PLCG1,PRKCA,PRKCD,PTK2,PTPN1,PTPN11,PTPN12,PTPN2,PTPN6,PTPRC,PTPRF,RAF1,RASA1,SH2B1,SH2B2,SHC1,SMAD2,SNX1,SNX2,SNX4,SNX6,SOCS1,SOCS2,SOCS3,SOCS6,SORBS1,SRC,STAT5A,STAT5B,SYNCRIP,VAV1,VAV3,YWHAB,AHSG,CAV1,CSK,ENPP1,FRS2,GRB10,GRB14,GRB2,GRB7,Grb14,HRAS,INPPL1,INSRR,IRS1,IRS2,JAK2,KHDRBS1,MAPK1,MAPK3,PRKCD,PTPN1,PTPN11,PTPN6,RASA1,SH2B1,SHC1,SMAD2,SNX1,SNX2,SNX4,SNX6,SOCS3,SORBS1,SYNCRIP,VAV1,VAV3