This is a synthetic peptide designed for use in combination with anti-IRAK3 antibody (Catalog #: ARP40709_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
IRAK3 contains 1 protein kinase domain and 1 death domain and belongs to the Ser/Thr protein kinase family, Pelle subfamily. It inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.
Alias Symbols: ASRT5, IRAKM
Protein Interaction Partner: IRAK1,IRAK2,IRAK3,MYD88,TICAM2,TRAF6,IRAK1,IRAK2,IRAK3,MYD88,TICAM2,TRAF6,MYD88,TRAF6