This is a synthetic peptide designed for use in combination with anti-IRF3 antibody (Catalog #: ARP31992_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
IRF3 is interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.IRF3 encodes interferon regulatory factor 3, a member of the interferon regulatory transcription factor (IRF) family. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes.
Protein Interaction Partner: CDKL2,CREBBP,CXCL10,E6,IRF3,CREBBP,EP300,GRIP1,IKBKE,IRF3,IRF5,IRF7,MAVS,PIAS4,PPIB,PRDX1,RELA,SERPINB2,SMURF2,SYT1,TBK1,TICAM1,TICAM2,CREBBP,DDX58,IKBKE,IRF5,IRF7,PPIP5K1,PRDX1,TANK,TBK1