KEAP1
(Kelch-Like ECH-Associated Protein 1 (KEAP1))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-KEAP1 antibody (Catalog #: ARP34727_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
KEAP1
Reactivité: Humain, Souris
Hôte: Synthetic
BP, BI
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
KEAP1
(Kelch-Like ECH-Associated Protein 1 (KEAP1))
Synonymes
INrf2 Peptide, KLHL19 Peptide, INRF2 Peptide, mKIAA0132 Peptide, Inrf2 Peptide, fb36f11 Peptide, keap1 Peptide, wu:fb36f11 Peptide, KEAP1 Peptide, klhl19 Peptide, zgc:171654 Peptide, kelch like ECH associated protein 1 Peptide, kelch-like ECH-associated protein 1 Peptide, Kelch-like ECH-associated protein 1 Peptide, kelch-like ECH-associated protein 1a Peptide, kelch like ECH associated protein 1 L homeolog Peptide, kelch-like ECH-associated protein 1b Peptide, KEAP1 Peptide, Keap1 Peptide, keap1a Peptide, keap1 Peptide, keap1.L Peptide, keap1b Peptide
Sujet
KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
Alias Symbols: INrf2, KLHL19
Protein Interaction Partner: BPTF,ETF1,FAM46A,MYO7A,NFE2L2,ARCN1,BBS1,BTRC,C10orf119,COPG,CUL3,ETF1,FAM123B,FAM129B,GABPA,GBAS,GET4,KIAA0564,MAD2L1,MAZ,MYO7A,NFE2L2,OSBPL10,PFAS,PGAM5,RBM45,SASS6,SLK,SQSTM1,TMEM160,TSC22D4,UBC,USP11,ZRANB1