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Melatonin Receptor 1A (MTNR1A) (C-Term) Peptide

MTNR1A Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN980355
  • Antigène Tous les produits Melatonin Receptor 1A (MTNR1A)
    Melatonin Receptor 1A (MTNR1A)
    Protein Region
    C-Term
    Origine
    Humain
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    GLLNQNFRKE YRRIIVSLCT ARVFFVDSSN DVADRVKWKP SPLMTNNNVV
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-MTNR1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    Melatonin Receptor 1A (MTNR1A)
    Synonymes
    MEL-1A-R Peptide, MT1 Peptide, MTNR1A Peptide, MR Peptide, MelR Peptide, MEL1A Peptide, Mel-1A-R Peptide, Mel-1A-R-A Peptide, Mel1a receptor A Peptide, mel1ar Peptide, mtnr1ar Peptide, zgc:110628 Peptide, melatonin receptor 1A Peptide, melatonin receptor 1A a Peptide, MTNR1A Peptide, Mtnr1a Peptide, mtnr1aa Peptide
    Sujet
    This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

    Alias Symbols: MEL-1A-R, MT1

    Protein Interaction Partner: MTNR1A,MTNR1B,CALR,CANX,CNP,DPM1,EEF1G,FLNA,GNA11,GNA13,GNAI1,GNAI2,GNAI3,GNB1,GNB4,GPR50,HNRNPA0,HSPA5,IRS4,LRRC59,MTNR1A,MTNR1B,PDIA6,PGRMC1,RAB10,RAC1,RAP1A,TMEM33,VAPB,GNA11,GNAI2,GNAI3

    Protein Size: 350
    Poids moléculaire
    39 kDa
    ID gène
    4543
    NCBI Accession
    NM_005958, NP_005949
    UniProt
    P48039
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