This is a synthetic peptide designed for use in combination with anti-MTNR1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.
Alias Symbols: MEL-1A-R, MT1
Protein Interaction Partner: MTNR1A,MTNR1B,CALR,CANX,CNP,DPM1,EEF1G,FLNA,GNA11,GNA13,GNAI1,GNAI2,GNAI3,GNB1,GNB4,GPR50,HNRNPA0,HSPA5,IRS4,LRRC59,MTNR1A,MTNR1B,PDIA6,PGRMC1,RAB10,RAC1,RAP1A,TMEM33,VAPB,GNA11,GNAI2,GNAI3