Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-PABPC1 antibody (Catalog #: ARP40403_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4, MIM 603407), and PABP3 (PABPC3, MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4, MIM 603407), and PABP3 (PABPC3, MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PAB1, PABP, PABP1, PABPC2, PABPL1
Protein Interaction Partner: ANAPC5,ATXN2,CARM1,CSDE1,EIF4B,EIF4G1,EIF4G3,GNB2L1,GSPT1,GSPT2,HNRNPD,NDRG1,PABPC1,PAIP1,PAIP2,PAIP2B,PAN2,PCBP1,PCBP2,PCSK7,PXN,SFRS12,STAU1,SYCP3,SYNCRIP,YWHAG,AIRE,ANAPC5,BCAR3,CNOT7,DYNLL1,EIF4A1,EIF4A2,EIF4B,EIF4G1,EIF4G3,ETF1,GNB2L1,GSPT1,GSPT2,HNRNPA1,IKBKE,PAIP1,PAIP2,PAN2,PAN3,PINX1,PUF60,PXN,TOB1,UPF1