Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-PKLR antibody (Catalog #: ARP41699_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
PKLR is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA).The protein encoded by this gene is a pyruvate kinase that catalyzes the production of phohsphoenolpyruvate from pyruvate and ATP. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Alternatively spliced transcript variants encoding distinct isoforms have been described.
Alias Symbols: PK1, PKL, RPK, PKR, PKRL
Protein Interaction Partner: MYOC,ARHGEF6,KIF23,OTUD5,PAK1,PXN,USP3,USPL1