This is a synthetic peptide designed for use in combination with anti-PSMA3 antibody (Catalog #: ARP57742_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA3 is a member of the peptidase T1A family, that is a 20S core alpha subunit.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.
Alias Symbols: HC8, MGC12306, MGC32631, PSC3
Protein Interaction Partner: ATN1,AURKB,BAT2,CDKN1A,CRYAB,CSNK2A1,EGR1,GFI1B,HHEX,PLK1,PRNP,PSMA1,PSMA2,PSMA4,PSMA6,PSMA7,PSMB5,RERE,SNRPB,SNRPF,STUB1,STX11,XRN2,BAT2,CDKN1A,CRYAB,EGR1,GIYD2,PLK1,PSMA1,PSMA6,PSMD13,PSMD14,SNRPB,SNRPF,STX11,TRIB3,XRN2