This is a synthetic peptide designed for use in combination with anti-SCNN1B antibody (Catalog #: ARP34936_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
When expressed in the bladder epithelium, the protein encoded by the SCNN1B gene might be implicated in the mechanosensory transduction in the bladder afferent pathways, thereby inducing detrusor instability by outlet obstruction. Common variants of this gene confer susceptibility to human essential hypertension.
Alias Symbols: BESC1, ENaCb, SCNEB, ENaCbeta
Protein Interaction Partner: ANK3,CNTN1,NEDD4,NEDD4L,NFASC,SCNN1A,SCNN1D,SCNN1G,STX1A,WWP2,HECW1,ITCH,NEDD4,NEDD4L,STX1A,UBC,WWP2