SMAD5
(SMAD, Mothers Against DPP Homolog 5 (SMAD5))
Origine
Humain
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
Attributs du produit
This is a synthetic peptide designed for use in combination with anti-SMAD5 antibody (Catalog #: ARP32006_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
SMAD5 undergoes copy number gain and increased expression, rather than loss of expression, and therefore does not act as a tumor-suppressor gene in hepatocellular carcinoma. Up-regulated Smad5 mediates apoptosis of gastric epithelial cells induced by Helicobacter pylori infection.
Alias Symbols: DWFC, JV5-1, MADH5
Protein Interaction Partner: ACVR1,BCAT1,BMP6,CXXC5,FLNA,GDF6,HBG2,HOXA13,HOXD13,MBD1,MEN1,MTMR10,PNKP,PPIL4,PSMD11,PTPN12,RBM4,RYR2,SF3B1,SFPQ,SMAD1,SMAD4,SMURF2,SNRNP70,SNRPA,SOX5,SOX7,SUV39H1,SUV39H2,TOB1,U2AF2,VPS24,WWP1,ZEB2,ZNF8,ACVR1,PLEKHO1,RUNX1,RUNX2,RUNX3,SMAD4,SMURF1,TOB1,Zfp128