T-Box 19 (TBX19) Peptide
TBX19
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits T-Box 19 (TBX19)
- T-Box 19 (TBX19)
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TBX19 antibody (Catalog #: ARP32364_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- T-Box 19 (TBX19)
- Synonymes
- TBX19 Peptide, TBS19 Peptide, TPIT Peptide, dJ747L4.1 Peptide, CH-TBXT Peptide, TBXT Peptide, AU019250 Peptide, D1Ertd754e Peptide, Tpit Peptide, T-box 19 Peptide, TBX19 Peptide, Tbx19 Peptide
- Sujet
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TBX19 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx19/Tpit gene. Studies in mouse show that Tpit protein is present only in the two pituitary pro-opiomelanocortin (POMC)-expressing lineages, the corticotrophs and melanotrophs. Mutations in the human ortholog were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene were found in patients with isolated deficiency of pituitary POMC-derived ACTH, suggesting an essential role for this gene in differentiation of the pituitary POMC lineage. ACTH deficiency is characterized by adrenal insufficiency symptoms such as weight loss, lack of appetite (anorexia), weakness, nausea, vomiting, and low blood pressure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ26302, FLJ34543, TBS 19, TBS19, TPIT, dJ747L4.1
Protein Interaction Partner: NR5A1
Protein Size: 448 - Poids moléculaire
- 48 kDa
- ID gène
- 9095
- NCBI Accession
- NM_005149, NP_005140
- UniProt
- O60806
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