Tryptophan Hydroxylase 2 (TPH2) (Middle Region) Peptide
TPH2
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits Tryptophan Hydroxylase 2 (TPH2)
- Tryptophan Hydroxylase 2 (TPH2)
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-TPH2 antibody (Catalog #: ARP34140_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- Tryptophan Hydroxylase 2 (TPH2)
- Synonymes
- ADHD7 Peptide, NTPH Peptide, Ntph Peptide, tphR Peptide, wu:fq15a04 Peptide, AU043594 Peptide, tryptophan hydroxylase 2 Peptide, tryptophan hydroxylase 2 (tryptophan 5-monooxygenase) Peptide, TPH2 Peptide, Tph2 Peptide, tph2 Peptide
- Sujet
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Tryptophan hydroxylase (TPH, EC 1.14.16.4) is the rate-limiting enzyme in the synthesis of serotonin (5-hydroxytryptamine, or 5HT). 5HT is causally involved in numerous central nervous activities, and it has several functions in peripheral tissues, including the maintenance of vascular tone and gut motility. This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. The human genome contains two related tryptophan hydroxylases, one on chromosome 11p15-p14 and one on chromosome 12q21. This gene is expressed predominantly in the brain stem. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by the mouse ortholog. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1805 AY098914.1 1-1805 1806-2360 AC090109.15 122981-123535
Alias Symbols: FLJ37295, MGC138871, MGC138872, NTPH, ADHD7
Protein Size: 490 - Poids moléculaire
- 56 kDa
- ID gène
- 121278
- NCBI Accession
- NM_173353, NP_775489
- UniProt
- Q8IWU9
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