PFKFB2 Produits
(6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))
Catégories
The protein encoded by this gene is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. The encoded protein has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. This protein regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories PFKFB2 en vedette
PFKFB2 Anticorps
High quality antibodies with extensive validation data.
PFKFB2 Kits ELISA
Reliable ELISA kits for a wide range of species.
PFKFB2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PFKFB2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7142693
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (3)
- (2)
N° du produit
ABIN392769
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (3)
N° du produit
ABIN6145483
Quantité
100 μL
Fiche technique
Fiche technique
PFKFB2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380333
Quantité
2 x 96 tests
Fiche technique
Fiche technique
PFKFB2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314736
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1314735
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN2728747
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PFKFB2
: "Label-free quantitative proteomic analysis of right ventricular remodeling in infant Tetralogy of Fallot patients." dans: Journal of proteomics, Vol. 84, pp. 78-91, (2013) (PubMed).: "Akt-dependent activation of the heart 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFKFB2) isoenzyme by amino acids." dans: The Journal of biological chemistry, Vol. 288, Issue 15, pp. 10640-51, (2013) (PubMed).
: "Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells." dans: BMC cancer, Vol. 10, pp. 638, (2010) (PubMed).
: "Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases." dans: The Journal of biological chemistry, Vol. 284, Issue 36, pp. 24223-32, (2009) (PubMed).
: "A role for PFK-2/FBPase-2, as distinct from fructose 2,6-bisphosphate, in regulation of insulin secretion in pancreatic beta-cells." dans: The Biochemical journal, Vol. 411, Issue 1, pp. 41-51, (2008) (PubMed).
: "Beta-catenin-mediated transactivation and cell-cell adhesion pathways are important in curcumin (diferuylmethane)-induced growth arrest and apoptosis in colon cancer cells." dans: Oncogene, Vol. 21, Issue 55, pp. 8414-27, (2002) (PubMed).
: "Isolation of novel heart-specific genes using the BodyMap database." dans: Genomics, Vol. 74, Issue 1, pp. 115-20, (2001) (PubMed).
Synonymes et noms alternatifs relatifs à PFKFB2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a (pfkfb2a), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (PFKFB2), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (pfkfb2), 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (Pfkfb2), 4930568D07Rik, PFK-2/FBPase-2, pfkfb2, RH2K, zgc:56282Protein level used designations for PFKFB2
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
- pfk-2/fbpase-2
- 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2-like
- 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2
- 6PF-2-K/Fru-2,6-P2ASE heart-type isozyme
- 6PF-2-K/Fru-2,6-P2ase 2
- PFK/FBPase 2
- PFKFB, cardiac
- fructose-2,6-bisphosphatase, cardiac isozyme
- 6PF-2-K/Fru-2,6-P2ase heart-type isozyme
- PFK-2/FBPase-2 gene B
- 6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 (heart)
- PFK-2/FBPase-2
- fructose 6-phosphate 2-kinase/fructose 2,6-bisphosphatase
- 6-phosphofructo-2-kinase /fructose-2,6-bisphosphatase
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