PHD1 Produits
(Egl-9 Family Hypoxia Inducible Factor 2 (EGLN2))
Catégories
The hypoxia inducible factor (HIF) is a transcriptional complex that is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this post-translational modification. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream RAB4B (RAB4B, member RAS oncogene family) gene. [provided by RefSeq, Feb 2011].
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Catégories PHD1 en vedette
PHD1 Anticorps
High quality antibodies with extensive validation data.
PHD1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PHD1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7151444
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
N° du produit
ABIN652648
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (3)
N° du produit
ABIN1679676
Quantité
100 μg
Fiche technique
Fiche technique
PHD1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6216907
Quantité
96 tests
Fiche technique
Fiche technique
PHD1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1352447
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
- (1)
N° du produit
ABIN2720027
Quantité
20 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3092321
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits PHD1
: "Tumor suppressor SPOP ubiquitinates and degrades EglN2 to compromise growth of prostate cancer cells." dans: Cancer letters, Vol. 390, pp. 11-20, (2017) (PubMed).: "Changes in Hypoxia-Inducible Factor-1 (HIF-1) and Regulatory Prolyl Hydroxylase (PHD) Enzymes Following Hypoxic-Ischemic Injury in the Neonatal Rat." dans: Neurochemical research, Vol. 41, Issue 3, pp. 515-22, (2016) (PubMed).
: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." dans: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).
: "EglN2 contributes to triple negative breast tumorigenesis by functioning as a substrate for the FBW7 tumor suppressor." dans: Oncotarget, Vol. 8, Issue 4, pp. 6787-6795, (2016) (PubMed).
: "PHD1 regulates p53-mediated colorectal cancer chemoresistance." dans: EMBO molecular medicine, Vol. 7, Issue 10, pp. 1350-65, (2015) (PubMed).
: "Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27." dans: Molecular cancer, Vol. 14, pp. 143, (2015) (PubMed).
: "EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer." dans: The EMBO journal, Vol. 34, Issue 23, pp. 2953-70, (2015) (PubMed).
: "Prolyl hydroxylation by EglN2 destabilizes FOXO3a by blocking its interaction with the USP9x deubiquitinase." dans: Genes & development, Vol. 28, Issue 13, pp. 1429-44, (2014) (PubMed).
: "Kaposi's sarcoma herpesvirus microRNAs induce metabolic transformation of infected cells." dans: PLoS pathogens, Vol. 10, Issue 9, pp. e1004400, (2014) (PubMed).
: "High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1α." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 1, pp. 206-17, (2014) (PubMed).
Synonymes et noms alternatifs relatifs à PHD1
egl-9 family hypoxia-inducible factor 1 (egln1), egl-9 family hypoxia inducible factor 2 (EGLN2), Egl nine homolog 2 (egln2), egl-9 family hypoxia-inducible factor 2 L homeolog (egln2.L), egl-9 family hypoxia-inducible factor 2 (Egln2), 0610011A13Rik, C85656, egln2, EIT6, Hif-p4h-1, HIF-PH1, HIFPH1, HPH-1, HPH-3, Ier4, PHD-1, PHD1, Phd1, phd2, SM-20Protein level used designations for PHD1
- EGL nine homolog 2
- egl nine homolog 2
- Egl nine homolog 2
- EGL nine (C.elegans) homolog 2
- egl nine homolog 2 (C. elegans)
- egl nine homolog 2-like
- HIF-PH1
- HIF-prolyl hydroxylase 1
- HPH-1
- falkor
- hypoxia-inducible factor prolyl hydroxylase 1
- immediate early response 4
- prolyl hydroxylase domain-containing protein 1
- HIF-1alpha prolyl-4-hydroxylase-1
- estrogen-induced tag 6
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