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PHKB Produits

(Phosphorylase Kinase, beta (PHKB))

Catégories

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.[provided by RefSeq, Feb 2010].

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Catégories PHKB en vedette

PHKB Anticorps

High quality antibodies with extensive validation data.

PHKB Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PHKB recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7163408
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
N° du produit ABIN6264179
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (1)
N° du produit ABIN562212
Quantité 50 μL
Fiche technique Fiche technique

PHKB recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5648029
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6208955
Quantité 96 tests
Fiche technique Fiche technique

PHKB recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314920
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3135952
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2728841
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PHKB

Oppermann, Gnad, Olsen, Hornberger, Greff, Kéri, Mann, Daub: "Large-scale proteomics analysis of the human kinome." dans: Molecular & cellular proteomics : MCP, Vol. 8, Issue 7, pp. 1751-64, (2009) (PubMed).

Beausoleil, Villén, Gerber, Rush, Gygi: "A probability-based approach for high-throughput protein phosphorylation analysis and site localization." dans: Nature biotechnology, Vol. 24, Issue 10, pp. 1285-92, (2006) (PubMed).

Wüllrich-Schmoll, Kilimann: "Structure of the human gene encoding the phosphorylase kinase beta subunit (PHKB)." dans: European journal of biochemistry / FEBS, Vol. 238, Issue 2, pp. 374-80, (1996) (PubMed).

Synonymes et noms alternatifs relatifs à PHKB

phosphorylase kinase regulatory subunit beta (PHKB), phosphorylase kinase beta (Phkb), phosphorylase kinase regulatory subunit beta (Phkb), AI463271

Protein level used designations for PHKB

  • phosphorylase b kinase regulatory subunit beta
  • phosphorylase kinase beta-subunit
  • phosphorylase kinase subunit beta
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