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Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Produits

(Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG))
This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008].

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Catégories Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide en vedette

Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Anticorps

High quality antibodies with extensive validation data.

Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN6145638
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IHC (p), IF
Validations
  • (6)
N° du produit ABIN1500202
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Monkey, Mouse
Application WB, IHC, IHC (p), IF
Validations
  • (7)
N° du produit ABIN1500203
Quantité 100 μL
Fiche technique Fiche technique

Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
N° du produit ABIN2728968
Quantité 20 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3094659
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3137255
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide

Huang, Cao, Ou, Yang, Zheng, Tang, Chen, Hu, Zheng, Wang: "The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma." dans: Molecular cancer, Vol. 17, Issue 1, pp. 93, (2018) (PubMed).

Hashimoto, Tanaka, Takeda, Ito, Nagano et al.: "Cilostazol Induces PGI2 Production via Activation of the Downstream Epac-1/Rap1 Signaling Cascade to Increase Intracellular Calcium by PLC? and to Activate p44/42 MAPK in Human Aortic Endothelial ..." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0132835, (2015) (PubMed).

Andreozzi, DAlessandris, Federici, Laratta, Del Guerra, Del Prato, Marchetti, Lauro, Perticone, Sesti et al.: "Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin ..." dans: Endocrinology, Vol. 145, Issue 6, pp. 2845-57, (2004) (PubMed).

Reddy, Lin, Huang, Samanta, Liao: "The IL-1 receptor accessory protein is essential for PI 3-kinase recruitment and activation." dans: Biochemical and biophysical research communications, Vol. 316, Issue 4, pp. 1022-8, (2004) (PubMed).

Chandrasekar, Mohanam, Gujrati, Olivero, Dinh, Rao: "Downregulation of uPA inhibits migration and PI3k/Akt signaling in glioblastoma cells." dans: Oncogene, Vol. 22, Issue 3, pp. 392-400, (2003) (PubMed).

François, Klotman: "Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages." dans: Journal of virology, Vol. 77, Issue 4, pp. 2539-49, (2003) (PubMed).

Reséndiz, Feng, Ji, Francis, Berndt, Kroll: "Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation." dans: Molecular pharmacology, Vol. 63, Issue 3, pp. 639-45, (2003) (PubMed).

Osaki, Kase, Adachi, Takeda, Hashimoto, Ito: "Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45." dans: Journal of cancer research and clinical oncology, Vol. 130, Issue 1, pp. 8-14, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (PIK3CG), phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (Pik3cg), phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma (pik3cg), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (pik3cg), phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma (Pik3cg), si:rp71-17i16.5 (si:rp71-17i16.5), 5830428L06Rik, p110gamma, p120-PI3K, PI3CG, PI3K, Pi3k, pi3k, PI3Kgamma, PIK3, wu:fb15d07, zgc:77033

Protein level used designations for Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide

  • 1-phosphatidylinositol 3-kinase
  • PI3-kinase subunit gamma
  • PI3K-gamma
  • p110-gamma
  • p110gamma
  • p120-PI3K
  • phosphatidylinositol 3 kinase gamma, p110 gamma
  • phosphatidylinositol 3-kinase catalytic 110-kD gamma
  • phosphatidylinositol 3-kinase, catalytic, gamma polypeptide
  • phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
  • phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • phosphoinositide-3-kinase gamma catalytic subunit
  • phosphoinositide-3-kinase, catalytic, gamma polypeptide
  • ptdIns-3-kinase subunit gamma
  • ptdIns-3-kinase subunit p110-gamma
  • serine/threonine protein kinase PIK3CG
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform-like
  • PI3Kgamma
  • catalytic subunit of G-beta-gamma-activated
  • phosphoinositide-3-kinase catalytic gamma polypeptide
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