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Phospholamban Produits

(Phospholamban (PLN))
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq, Jul 2008].

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Catégories Phospholamban en vedette

Phospholamban Anticorps

High quality antibodies with extensive validation data.

Phospholamban Kits ELISA

Reliable ELISA kits for a wide range of species.

Phospholamban Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Phospholamban recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (8)
N° du produit ABIN7442687
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB, IHC, FACS
Validations
  • (5)
N° du produit ABIN3032226
Quantité 0.4 mL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validations
  • (2)
N° du produit ABIN682468
Quantité 100 μL
Fiche technique Fiche technique

Phospholamban recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969290
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958555
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1571936
Quantité 96 tests
Fiche technique Fiche technique

Phospholamban recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1315443
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7412563
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7395149
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Phospholamban

Jin, Nesbitt, Yang, Chen, Horowitz, Jones, Vandergaast, Carey, Reiter, Russell, Kyratsous, Hooper, Hamilton, Ferreira, Deng, Straus, Baras, Hillyer, Luchsinger: "Seroprevalence of anti-SARS-CoV-2 antibodies in a cohort of New York City metro blood donors using multiple SARS-CoV-2 serological assays: Implications for controlling the epidemic and "Reopening"." dans: PloS one, Vol. 16, Issue 4, pp. e0250319, (2021) (PubMed).

Stathopoulou, Schobesberger, Bork, Sprenger, Perera, Sotoud, Geertz, David, Christ, Nikolaev, Cuello: "Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes." dans: Cellular signalling, Vol. 63, pp. 109362, (2019) (PubMed).

Kushnir, Santulli, Reiken, Coromilas, Godfrey, Brunjes, Colombo, Yuzefpolskaya, Sokol, Kitsis, Marks: "Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure." dans: Circulation, Vol. 138, Issue 11, pp. 1144-1154, (2019) (PubMed).

Rigatti, Le, Gerber, Moraru, Dodge-Kafka: "Phosphorylation state-dependent interaction between AKAP7δ/γ and phospholamban increases phospholamban phosphorylation." dans: Cellular signalling, Vol. 27, Issue 9, pp. 1807-15, (2015) (PubMed).

Kienesberger, Pulinilkunnil, Sung, Nagendran, Haemmerle, Kershaw, Young, Light, Oudit, Zechner, Dyck: "Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction." dans: Molecular and cellular biology, Vol. 32, Issue 4, pp. 740-50, (2012) (PubMed).

Møller, Pham, Gustafsson, Hedley, Ersbøll, Bundgaard, Andersen, Torp-Pedersen, Køber, Christiansen: "The role of Lamin A/C mutations in Danish patients with idiopathic dilated cardiomyopathy." dans: European journal of heart failure, Vol. 11, Issue 11, pp. 1031-5, (2009) (PubMed).

Prasad, Inesi: "Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes." dans: American journal of physiology. Cell physiology, Vol. 296, Issue 5, pp. C992-C1002, (2009) (PubMed).

Pantos, Mourouzis, Markakis, Dimopoulos, Xinaris, Kokkinos, Panagiotou, Cokkinos: "Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats." dans: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 32, Issue 2, pp. 333-9, (2007) (PubMed).

Rodriguez, Kranias: "Phospholamban: a key determinant of cardiac function and dysfunction." dans: Archives des maladies du coeur et des vaisseaux, Vol. 98, Issue 12, pp. 1239-43, (2006) (PubMed).

Kaliman, Catalucci, Lam, Kondo, Gutiérrez, Reddy, Palacín, Zorzano, Chien, Ruiz-Lozano: "Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum." dans: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8016-21, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à Phospholamban

phospholamban (PLN), phospholamban (pln), phospholamban (Pln), cmd1p, CMD1P, CMH18, LOC100226261, plb, PLB, Plb, Plm

Protein level used designations for Phospholamban

  • phospholamban
  • cardiac phospholamban
  • PLB
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