Phospholamban Produits
(Phospholamban (PLN))
Catégories
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure. [provided by RefSeq, Jul 2008].
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Catégories Phospholamban en vedette
Phospholamban Anticorps
High quality antibodies with extensive validation data.
Phospholamban Kits ELISA
Reliable ELISA kits for a wide range of species.
Phospholamban Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Phospholamban recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7442687
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, WB, IHC, FACS
Validations
- (5)
N° du produit
ABIN3032226
Quantité
0.4 mL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro)
Validations
- (2)
N° du produit
ABIN682468
Quantité
100 μL
Fiche technique
Fiche technique
Phospholamban recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969290
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958555
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1571936
Quantité
96 tests
Fiche technique
Fiche technique
Phospholamban recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315443
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7412563
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7395149
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Phospholamban
: "Seroprevalence of anti-SARS-CoV-2 antibodies in a cohort of New York City metro blood donors using multiple SARS-CoV-2 serological assays: Implications for controlling the epidemic and "Reopening"." dans: PloS one, Vol. 16, Issue 4, pp. e0250319, (2021) (PubMed).: "Divergent off-target effects of RSK N-terminal and C-terminal kinase inhibitors in cardiac myocytes." dans: Cellular signalling, Vol. 63, pp. 109362, (2019) (PubMed).
: "Ryanodine Receptor Calcium Leak in Circulating B-Lymphocytes as a Biomarker in Heart Failure." dans: Circulation, Vol. 138, Issue 11, pp. 1144-1154, (2019) (PubMed).
: "Phosphorylation state-dependent interaction between AKAP7δ/γ and phospholamban increases phospholamban phosphorylation." dans: Cellular signalling, Vol. 27, Issue 9, pp. 1807-15, (2015) (PubMed).
: "Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction." dans: Molecular and cellular biology, Vol. 32, Issue 4, pp. 740-50, (2012) (PubMed).
: "The role of Lamin A/C mutations in Danish patients with idiopathic dilated cardiomyopathy." dans: European journal of heart failure, Vol. 11, Issue 11, pp. 1031-5, (2009) (PubMed).
: "Effects of thapsigargin and phenylephrine on calcineurin and protein kinase C signaling functions in cardiac myocytes." dans: American journal of physiology. Cell physiology, Vol. 296, Issue 5, pp. C992-C1002, (2009) (PubMed).
: "Thyroid hormone attenuates cardiac remodeling and improves hemodynamics early after acute myocardial infarction in rats." dans: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 32, Issue 2, pp. 333-9, (2007) (PubMed).
: "Phospholamban: a key determinant of cardiac function and dysfunction." dans: Archives des maladies du coeur et des vaisseaux, Vol. 98, Issue 12, pp. 1239-43, (2006) (PubMed).
: "Myotonic dystrophy protein kinase phosphorylates phospholamban and regulates calcium uptake in cardiomyocyte sarcoplasmic reticulum." dans: The Journal of biological chemistry, Vol. 280, Issue 9, pp. 8016-21, (2005) (PubMed).
Synonymes et noms alternatifs relatifs à Phospholamban
phospholamban (PLN), phospholamban (pln), phospholamban (Pln), cmd1p, CMD1P, CMH18, LOC100226261, plb, PLB, Plb, PlmProtein level used designations for Phospholamban
- phospholamban
- cardiac phospholamban
- PLB
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