Phospholipase C gamma 1 Produits
(phospholipase C, gamma 1 (PLCG1))
Catégories
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories Phospholipase C gamma 1 en vedette
Phospholipase C gamma 1 Anticorps
High quality antibodies with extensive validation data.
Phospholipase C gamma 1 Kits ELISA
Reliable ELISA kits for a wide range of species.
Phospholipase C gamma 1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Phospholipase C gamma 1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, PLA
Validations
- (1)
- (7)
N° du produit
ABIN562265
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (7)
N° du produit
ABIN7431485
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (6)
N° du produit
ABIN6256799
Quantité
100 μL
Fiche technique
Fiche technique
Phospholipase C gamma 1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
- (3)
N° du produit
ABIN6730785
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969307
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958575
Quantité
96 tests
Fiche technique
Fiche technique
Phospholipase C gamma 1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315336
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7389746
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN2967705
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Phospholipase C gamma 1
: "Osteoblasts secrete Cxcl9 to regulate angiogenesis in bone." dans: Nature communications, Vol. 7, pp. 13885, (2018) (PubMed).: "mTORC1 activation downregulates FGFR3 and PTH/PTHrP receptor in articular chondrocytes to initiate osteoarthritis." dans: Osteoarthritis and cartilage, Vol. 25, Issue 6, pp. 952-963, (2018) (PubMed).
: "Olaquindox disrupts tight junction integrity and cytoskeleton architecture in mouse Sertoli cells." dans: Oncotarget, Vol. 8, Issue 51, pp. 88630-88644, (2017) (PubMed).
: "PLC-? and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras." dans: Science signaling, Vol. 6, Issue 304, pp. ra105, (2013) (PubMed).
: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).
: "Signal regulatory protein ? negatively regulates mast-cell activation following Fc?RI aggregation." dans: European journal of immunology, Vol. 43, Issue 6, pp. 1598-607, (2013) (PubMed).
: "Down-regulation of miR-218-2 and its host gene SLIT3 cooperate to promote invasion and progression of thyroid cancer." dans: The Journal of clinical endocrinology and metabolism, Vol. 98, Issue 8, pp. E1334-44, (2013) (PubMed).
: "Inhibition of vascular smooth muscle cell proliferation by the vitamin E derivative pentamethylhydroxychromane in an in vitro and in vivo study: pivotal role of hydroxyl radical-mediated PLCgamma1 ..." dans: Free radical biology & medicine, Vol. 49, Issue 5, pp. 881-93, (2010) (PubMed).
: "Multiple host proteins that function in phosphatidylinositol-4-phosphate metabolism are recruited to the chlamydial inclusion." dans: Infection and immunity, Vol. 78, Issue 5, pp. 1990-2007, (2010) (PubMed).
: "CCR7/CCL21 migration on fibronectin is mediated by phospholipase Cgamma1 and ERK1/2 in primary T lymphocytes." dans: The Journal of biological chemistry, Vol. 285, Issue 50, pp. 38781-7, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à Phospholipase C gamma 1
phospholipase C gamma 1 (PLCG1), phospholipase C gamma 1 L homeolog (plcg1.L), 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (LOC100633163), phospholipase C, gamma 1 (Plcg1), phospholipase C gamma 1 (Plcg1), phospholipase C, gamma 1 (plcg1), AI894140, Cded, fj46f04, NCKAP3, nckap3, Plc-1, Plc-gamma1, PLC-II, plc-ii, PLC1, plc1, PLC148, plc148, Plcg-1, PLCgamma1, plcgamma1, PPLCA, wu:fj46f04, wu:fj57a05Protein level used designations for Phospholipase C gamma 1
- 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
- 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1
- 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1
- PLC-148
- PLC-gamma-1
- inositoltrisphosphohydrolase
- monophosphatidylinositol phosphodiesterase
- phosphatidylinositol phospholipase C
- phosphoinositidase C
- phosphoinositide phospholipase C
- phosphoinositide phospholipase C-gamma-1
- phospholipase C, gamma 1 (formerly subtype 148)
- phospholipase C-148
- phospholipase C-II
- phospholipase C-gamma-1
- triphosphoinositide phosphodiesterase
- PLC gamma 1
- phospholipase C-gamma-1b
- phospholipase C, gamma 1
- PLC-II
- cell differentiation and embryonic development
- dead beat
- ded
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